MRPL11
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Official Full Name
mitochondrial ribosomal protein L11 -
Overview
A subset of mitochondrial proteins are synthesized on the ribosomes within mitochondria. The 55S mammalian mitochondrial ribosomes are composed of a 28S small subunit and a 39S large subunit. Over 40 protein components have been identified from the large -
Synonyms
MRPL11;mitochondrial ribosomal protein L11;39S ribosomal protein L11, mitochondrial;L11MT;CGI-113;MRP-L11;MGC111024
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- His&SUMO
- GST
- Flag
Involved Pathway
MRPL11 involved in several pathways and played different roles in them. We selected most pathways MRPL11 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | RPL6,RPL10L,RPL8,RPS3,MRPS14,RPS11,RPS8A,RPS26,MRPS9,RPS9 |
Protein Function
MRPL11 has several biochemical functions, for example, poly(A) RNA binding,protein binding,rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL11 itself. We selected most functions MRPL11 had, and list some proteins which have the same functions with MRPL11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DNMT1,CDKN1B,NPBWR1,PAWR,FAM83A,SPINLW1,SYCP1,APPB,PKHD1L1,OPRL1 |
| structural constituent of ribosome | MRPS7,RPL31,MRPS6,RPL21,RPS23,RPL5B,RPL34,MRPL37,MRPS18B,RPS27.1 |
| poly(A) RNA binding | CNOT1,MTO1,EMG1,SUPV3L1,RBM34,RBM8A,KIAA1324,PUS7,NSUN5,MYH9 |
| rRNA binding | DDX21,MRPL16,PPAN,FASTKD5,RPS5,MRPS17,RPL12,RPS4X,MRPS7,DDX28 |
Interacting Protein
MRPL11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL11.
FSD2;gag;TFCP2;CAMK2B;CAMK2D;KRT40;HMBOX1
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References
- Yoon, JC; Ling, AJY; et al. GLTSCR2/PICT1 links mitochondrial stress and Myc signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:3781-3786(2014).
- Han, MJ; Cimen, H; et al. Purification of human mitochondrial ribosomal L7/L12 stalk proteins and reconstitution of functional hybrid ribosomes in Escherichia coli. PROTEIN EXPRESSION AND PURIFICATION 78:48-54(2011).
