MPZ

  • Official Full Name

    myelin protein zero

  • Overview

    This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. [provided by RefSeq, Apr 2010]

  • Synonyms

    MPZ;myelin protein zero;P0;CHM;DSS;MPP;CMT1;CMT1B;CMT2I;CMT2J;CMT4E;CMTDI3;CMTDID;HMSNIB;myelin protein P0;myelin peripheral protein;Charcot-Marie-Tooth neuropathy 1B

Recombinant Proteins

  • Human
  • Rat
  • Zebrafish
  • Mouse
  • Heterodontus francisci (Horn shark) (Cestracion francisci)
  • Xenopus laevis
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Mus musculus
  • Bovine
  • Chicken
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • Yeast
  • In Vitro Cell Free System
  • His
  • Non
  • Myc&DDK
  • GST
  • His&GST
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
MPZ-2294H Recombinant Human MPZ protein, His-tagged E.coli Human His Ile30~Lys248
MPZ-29152TH Recombinant Human MPZ Wheat Germ Human Non 258 amino acids
MPZ-3744R Recombinant Rat MPZ Protein Mammalian Cells Rat His
MPZ-3902H Recombinant Human MPZ protein, MYC/DDK-tagged HEK293 Human Myc&DDK
MPZ-8493H Recombinant Human MPZ protein, His-tagged HEK293 Human His Ile30-Arg153
MPZ-9712Z Recombinant Zebrafish MPZ Mammalian Cells Zebrafish His
MPZ-4219HCL Recombinant Human MPZ 293 Cell Lysate HEK293 Human Non
MPZ-1218H Recombinant Human MPZ Protein (30-156 aa), GST-tagged E.coli Human GST 30-156 aa
MPZ-1461H Recombinant Human MPZ Protein (30-156 aa), His-tagged Yeast Human His 30-156 aa
Mpz-1791R Recombinant Rat Mpz Protein, His&GST-tagged E.coli Rat His&GST Ile30-Lys248
MPZ-314HF Recombinant Full Length Human MPZ Protein In Vitro Cell Free System Human Full L. 258 amino acids
MPZ-3239H Recombinant Human MPZ protein, His-tagged E.coli Human His 30-156aa
MPZ-3402R Recombinant Rat MPZ Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
MPZ-3402R-B Recombinant Rat MPZ Protein Pre-coupled Magnetic Beads HEK293 Rat
Mpz-4131M Recombinant Mouse Mpz Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK
MPZ-4599H Recombinant Human MPZ Protein (Ile30-Arg153), C-His tagged Mammalian Cells Human His Ile30-Arg153
MPZ-4600H Recombinant Human MPZ Protein (Ile30-Lys248), His tagged E.coli Human His Ile30-Lys248
MPZ-5524H Recombinant Human MPZ Protein, GST-tagged Wheat Germ Human GST
MPZ-6337HF Recombinant Full Length Human MPZ Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 258 amino acids
RFL13370RF Recombinant Full Length Rat Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Rat His Full L. Full Length of Mature Protein (30-248)
RFL15417HF Recombinant Full Length Heterodontus Francisci Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Heterodontus francisci (Horn shark) (Cestracion francisci) His Full L. Full Length of Mature Protein (28-246)
RFL16682HF Recombinant Full Length Human Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Human His Full L. Full Length of Mature Protein (30-248)
RFL19715XF Recombinant Full Length Xenopus Laevis Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Xenopus laevis His Full L. Full Length of Mature Protein (29-245)
RFL22345XF Recombinant Full Length Xenopus Tropicalis Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) His Full L. Full Length of Mature Protein (27-243)
RFL29226MF Recombinant Full Length Mouse Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Mus musculus His Full L. Full Length of Mature Protein (30-248)
RFL31068BF Recombinant Full Length Bovine Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Bovine His Full L. Full Length of Mature Protein (29-248)
RFL34972GF Recombinant Full Length Chicken Myelin Protein P0(Mpz) Protein, His-Tagged E.coli Chicken His Full L. Full Length of Mature Protein (30-249)

    Involved Pathway

    MPZ involved in several pathways and played different roles in them. We selected most pathways MPZ participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with MPZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) ITGB8,H2-AA,CDH4,BLB2,OCLNB,MHC2DAB,PRPSAP2,JAM2,CNTNAP2A,PTPRC

    Protein Function

    MPZ has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MPZ itself. We selected most functions MPZ had, and list some proteins which have the same functions with MPZ. You can find most of the proteins on our site.

    Function Related Protein
    structural molecule activity IVL,KRT39,IFFO2,KRT81,CDC42SE1,MTAP7D3,CAV1,CLDN7B,CYT1L,KRT4

    Interacting Protein

    MPZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPZ here. Most of them are supplied by our site. Hope this information will be useful for your research of MPZ.

    CCP110;PSMB3;PINX1

    Resources

    References

    • Yamaguchi, Y; Hayashi, A; et al. L-MPZ, a Novel Isoform of Myelin P0, Is Produced by Stop Codon Readthrough. JOURNAL OF BIOLOGICAL CHEMISTRY 287:17765-17776(2012).
    • Bai, Q; Sun, M; et al. Major Isoform of Zebrafish P0 Is a 23.5 KDa Myelin Glycoprotein Expressed in Selected White Matter Tracts of the Central Nervous System. JOURNAL OF COMPARATIVE NEUROLOGY 519:1580-1596(2011).

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