MPG
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Official Full Name
N-methylpurine-DNA glycosylase -
Overview
DNA-3-methyladenine glycosylase is an enzyme that in humans is encoded by the MPG gene. -
Synonyms
MPG;N-methylpurine-DNA glycosylase;DNA-3-methyladenine glycosylase;alkyladenine DNA glycosylase;MDG;3-alkyladenine DNA glycosylase;3-methyladenine DNA glycosidase;proliferation-inducing protein 11;proliferation-inducing protein 16;N-methylpurine-
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- Yeast
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- Non
- His&T7
- GST
- His&Fc&Avi
Involved Pathway
MPG involved in several pathways and played different roles in them. We selected most pathways MPG participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Base excision repair | nth,PNKP,LIG3,POLE,HMGB1,APEX1,PCNA,PARP4,POLD4,HMGB1A |
Protein Function
MPG has several biochemical functions, for example, DNA-3-methyladenine glycosylase activity,DNA-3-methylguanine glycosylase activity,DNA-7-methyladenine glycosylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MPG itself. We selected most functions MPG had, and list some proteins which have the same functions with MPG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MECP2,ORMDL3,DOCK4,ACBD3,RTN1,FKBP2,DMAP1,HMGA2,CTDSP1,LSM5 |
| damaged DNA binding | TDG,FEN1,ERCC4,DCLRE1C,BRCA1,DCLRE1A,H2AFX,CRY2,XRCC6,RPS3 |
Interacting Protein
MPG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPG here. Most of them are supplied by our site. Hope this information will be useful for your research of MPG.
PRNP;HSD17B14;4504555;PGRMC1;NUDT21;GOT2;SOD2;ETFA;MIF;RPL35A;XRCC1;GSTM3;FBLN1;ACAT1;PSMA1
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References
- Beetson, KA; Smith, SF; et al. Vasa Nervorum in Rat Major Pelvic Ganglion are Innervated by Nitrergic Nerve Fibers. JOURNAL OF SEXUAL MEDICINE 10:2967-2974(2013).
- Baboci, L; Boscolo-Rizzo, P; et al. Evidence of the causal role of human papillomavirus type 58 in an oropharyngeal carcinoma. VIROLOGY JOURNAL 10:-(2013).
