MOB1A
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Official Full Name
MOB kinase activator 1A -
Overview
MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. Its Drosophila and mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumo -
Synonyms
MOB1A;MOB kinase activator 1A;C2orf6, chromosome 2 open reading frame 6 , MOB1 Mps One Binder homolog A (yeast) , MOB1, Mps One Binder kinase activator like 1B (yeast) , MOBK1B, MOBKL1B;FLJ10788;FLJ11595;Mats1;MOB1;Mob4B;mob1 alpha;mob1 homolo
Recombinant Proteins
- Zebrafish
- Human
- Rat
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Avi&Fc&His
- DDK&Myc
- His&SUMO
- GST
Involved Pathway
MOB1A involved in several pathways and played different roles in them. We selected most pathways MOB1A participated on our site, such as Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOB1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hippo signaling pathway | CTNNA3,BMPR2,FZD6,SERPINE1,BMP8B,SCRIB,GDF7,ACTB,FZD10,WNT8B |
Protein Function
MOB1A has several biochemical functions, for example, metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOB1A itself. We selected most functions MOB1A had, and list some proteins which have the same functions with MOB1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF684,SNAI2,F13A1,B3GAT1,ZNF445,TPH1B,PMELA,DNAJA3A,ZNHIT2,CSH1 |
| protein binding | EGF,TANK,LY96,SUN1,KCNA2,RNF10,GAGE8,LAT2,PTPN3,KLHDC3 |
Interacting Protein
MOB1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOB1A here. Most of them are supplied by our site. Hope this information will be useful for your research of MOB1A.
STK38L;STK4;LATS1
MOB1A Related Signal Pathway
Resources
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References
- Pinosa, F; Begheldo, M; et al. The Arabidopsis thaliana Mob1A gene is required for organ growth and correct tissue patterning of the root tip. ANNALS OF BOTANY 112:1803-1814(2013).
- Couzens, AL; Knight, JDR; et al. Protein Interaction Network of the Mammalian Hippo Pathway Reveals Mechanisms of Kinase-Phosphatase Interactions. SCIENCE SIGNALING 6:-(2013).
