MND1
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Official Full Name
meiotic nuclear divisions 1 homolog (S. cerevisiae) -
Overview
The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA;and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 (PubMed;17639080)). Both the MND1 and HOP2 genes are indispensable for meiotic recombination. -
Synonyms
MND1;meiotic nuclear divisions 1 homolog (S. cerevisiae);meiotic nuclear division protein 1 homolog;GAJ;2610034E18Rik;AI591601;GAJ protein;Homolog of yeast MND1;Meiotic nuclear division 1, S. cerevisiae. homolog of;Meiotic nuclear divisions 1 homolog;MGC134110;RGD1309007
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MND1-923H | Recombinant Human MND1, GST-tagged | E.coli | Human | GST | 1-205aa | |
| MND1-1024Z | Recombinant Zebrafish MND1 | Mammalian Cell | Zebrafish | His |
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| MND1-2796R | Recombinant Rhesus monkey MND1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| MND1-4621C | Recombinant Chicken MND1 | Mammalian Cell | Chicken | His |
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| MND1-9934M | Recombinant Mouse MND1 Protein | Mammalian Cell | Mouse | His |
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| MND1-678HCL | Recombinant Human MND1 cell lysate | Human | Non |
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| MND1-2616R | Recombinant Rhesus Macaque MND1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MND1-2616R-B | Recombinant Rhesus Macaque MND1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| MND1-4669H | Recombinant Human MND1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MND1-5216HF | Recombinant Full Length Human MND1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 205 amino acids |
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| MND1-5612M | Recombinant Mouse MND1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MND1-5612M-B | Recombinant Mouse MND1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MND1 involved in several pathways and played different roles in them. We selected most pathways MND1 participated on our site, such as Cell Cycle,Meiosis,Meiotic recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with MND1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Meiosis | TERF2IP,MSH5,STAG1,TERF1,TEX12,STAG2,DMC1,POT1,TINF2,FKBP6 |
| Cell cycle | CDK7,SGOL2,PCM1,CDC20,FGFR1OP,MCM6L,RAD9A,GINS3,TUBB4A,ANAPC7 |
| Meiotic recombination | MSH5,TEX15,PSMC3IP,MSH4,SPO11,DMC1 |
Protein Function
MND1 has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MND1 itself. We selected most functions MND1 had, and list some proteins which have the same functions with MND1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | RPAP1,ZSCAN4C,NUP153,SP110,GON4L,ZNF285A,IRF3,RORAB,HIF1AL,RXRAB |
Interacting Protein
MND1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MND1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MND1.
IK;PSMC3IP
Resources
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References
- Cho, NW; Dilley, RL; et al. Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis. CELL 159:108-121(2014).
- Chan, YL; Brown, MS; et al. The Third Exon of the Budding Yeast Meiotic Recombination Gene HOP2 Is Required for Calcium-dependent and Recombinase Dmc1-specific Stimulation of Homologous Strand Assimilation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:18076-18086(2014).
