MNAT1
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Official Full Name
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) -
Synonyms
MNAT1;menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis);7181;ENSG00000020426;MAT1;TFB3;CAP35;RNF66;14q23;CDK-activating kinase assembly factor MAT1;CDK-activating kinase assembly factor MAT1;RING finger protein 66;RING finger protein MAT1;CDK7/cyclin-H assembly factor;cyclin G1 interacting protein;cyclin-G1-interacting protein;menage a trois 1 (CAK assembly factor)
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Human
- Mouse
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
- GST
Involved Pathway
MNAT1 involved in several pathways and played different roles in them. We selected most pathways MNAT1 participated on our site, such as Basal transcription factors,Nucleotide excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with MNAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Basal transcription factors | TAF12,TAF13,TAF8,GTF2A1,GTF2H1,CCNH,TAF4B,GTF2H5,TAF6L,TAF11 |
Nucleotide Excision Repair | POLD2,POLD1,RBX1,ERCC2,XPC,COPS7A,POLE,ACTR5,YY1A,MCRS1 |
Protein Function
MNAT1 has several biochemical functions, for example, contributes_to DNA-dependent ATPase activity,contributes_to RNA polymerase II carboxy-terminal domain kinase activity,protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MNAT1 itself. We selected most functions MNAT1 had, and list some proteins which have the same functions with MNAT1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
contributes_to DNA-dependent ATPase activity | GTF2H2,GTF2H4,ERCC2,GTF2H3,GTF2H1,ERCC3,RBBP4,BPTF |
contributes_to RNA polymerase II carboxy-terminal domain kinase activity | GTF2H3,GTF2H2,ERCC3,GTF2H4,ERCC2,GTF2H1 |
protein N-terminus binding | KCNIP1,STXBP1,RPA2,BIRC2,RPA3,PHB2,CSNK2A2,SCFD1,SNF8,TAF11 |
zinc ion binding | MGRN1A,HLTF,PYGO1,KDM2A,NPLOC4,CXXC5,FTR72,ESR1,ADAMTS2,PPARD |
protein binding | GNG10,PLCE1,TBKBP1,ARMC9,XRCC4,RTN4,HMOX1,SMURF1,AKAP17A,MAP3K1 |
Interacting Protein
MNAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MNAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MNAT1.
CCNH;CDK7;MDM4;TRIM21;BRCA1;EEF1A1;NGFRAP1;TRIM26;MKRN3;RBM48;RIF1;COPS6;HPS6;TRIML1;TSC1
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References
- de Souza, Edmarcia Elisa; Meirelles, Gabriela Vaz; et al. Characterization of the Human NEK7 Interactome Suggests Catalytic and Regulatory Properties Distinct from Those of NEK6. JOURNAL OF PROTEOME RESEARCH 13:4074-4090(2014).
- Moslehi, Roxana; Ambroggio, Xavier; et al. Nucleotide excision repair/transcription gene defects in the fetus and impaired TFIIH-mediated function in transcription in placenta leading to preeclampsia. BMC GENOMICS 15:-(2014).