MLLT10
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Official Full Name
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -
Overview
This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MLLT10;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila);translocated to, 10;myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog);protein AF-10;AF10;type I AF10 protein;type IV AF
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MLLT10-9885M | Recombinant Mouse MLLT10 Protein | Mammalian Cells | Mouse | His |
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| MLLT10-4293HCL | Recombinant Human MLLT10 293 Cell Lysate | HEK293 | Human | Non |
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| MLLT10-5391H | Recombinant Human MLLT10 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MLLT10-5584M | Recombinant Mouse MLLT10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MLLT10-5584M-B | Recombinant Mouse MLLT10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
MLLT10 involved in several pathways and played different roles in them. We selected most pathways MLLT10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MLLT10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MLLT10 has several biochemical functions, for example, DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLLT10 itself. We selected most functions MLLT10 had, and list some proteins which have the same functions with MLLT10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | GBX2,PRRXL1,ZEB1,EGR2A,ZFP39,ZNF397,SMAD1,ZNF480,NR1D1,FOXI3B |
| zinc ion binding | PIAS4,MEP1A.2,Car12,BTR22,RNF25,TRIM43C,RNF14,BAZ1A,SOD1,TRAF4A |
| DNA binding | FUS,DLX3B,ESR2A,FOXD5,RX3,SURF6,FOSB,ZNF670,ZNF559,CHD4A |
| protein binding | PRKAA2,LAT2,MEI4,SOX-2,OSBPL2,RPP25,MLH1,DDB1,SIRT2,CRH |
Interacting Protein
MLLT10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLLT10 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLLT10.
DOT1L;CTNNB1;NDEL1;TMPO;MLLT3;MLLT6;SKP1;Ube2i;MLLT1;Naa50;Scai;Mta1;ZNF526;Mllt1
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References
- Baird, JH; Minniti, CP; et al. Oscillatory haematopoiesis in adults with sickle cell disease treated with hydroxycarbamide. BRITISH JOURNAL OF HAEMATOLOGY 168:737-746(2015).
- Lohsen, S; Majumder, P; et al. Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types. GENES AND IMMUNITY 15:543-555(2014).
