MLL3
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Official Full Name
myeloid/lymphoid or mixed-lineage leukemia 3 -
Overview
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. -
Synonyms
MLL3;myeloid/lymphoid or mixed-lineage leukemia 3;histone-lysine N-methyltransferase MLL3;HALR;KIAA1506;KMT2C;Homologous to ALR protein;Lysine N-methyltransferase 2C;MLL3_HUMAN;Myeloid/lymphoid or mixed-lineage leukemia protein 3;Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog;ALR-like protein;OTTHUMP00000197821;histone-lysine N-methyltransferase, H3 lysine-4 specific
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MLL3-191H |
Active Recombinant Human MLL3 protein, GST-tagged
|
Insect Cells | Human | GST | 4689-end |
|
Involved Pathway
MLL3 involved in several pathways and played different roles in them. We selected most pathways MLL3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MLL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MLL3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MLL3 itself. We selected most functions MLL3 had, and list some proteins which have the same functions with MLL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
MLL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLL3.
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References
- Yamamoto, H; Watanabe, Y; et al. An updated review of gastric cancer in the next-generation sequencing era: Insights from bench to bedside and vice versa. WORLD JOURNAL OF GASTROENTEROLOGY 20:3927-3937(2014).
- Daniel, JA; Santos, MA; et al. PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination. SCIENCE 329:917-923(2010).
