MLF1
-
Official Full Name
myeloid leukemia factor 1 -
Overview
This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
MLF1;myeloid leukemia factor 1;myeloid leukemia factor 1 variant 1;myeloid leukemia factor 1 variant 2;myeloid leukemia factor 1 variant 3;Hls7;MLF1_HUMAN;Myelodysplasia myeloid leukemia factor 1;Myelodysplasia-myeloid leukemia factor 1;OTTHUMP00000213453;OTTHUMP00000213454;OTTHUMP00000213483;OTTHUMP00000213484;OTTHUMP00000213485;OTTHUMP00000213486;OTTHUMP00000213487;OTTHUMP00000213488;OTTHUMP00000213492;OTTHUMP00000213493;OTTHUMP00000213494
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- T7
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MLF1-149H | Recombinant Human MLF1 protein, T7-tagged | E.coli | Human | T7 | 268 a.a. |
|
| MLF1-2390H | Recombinant Human MLF1 protein, GST-tagged | Wheat Germ | Human | GST | 1-268 a.a. |
|
| MLF1-2780R | Recombinant Rhesus monkey MLF1 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| MLF1-29154TH | Recombinant Human MLF1, T7 -tagged | E.coli | Human | T7 | Full L. |
|
| MLF1-2944H | Recombinant Human Myeloid Leukemia Factor 1, T7-tagged | E.coli | Human | T7 | 1-268 a.a. |
|
| MLF1-3438H | Recombinant Human MLF1 protein, His-tagged | E.coli | Human | His | 1-268 a.a. |
|
| MLF1-4297HCL | Recombinant Human MLF1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| MLF1-2601R | Recombinant Rhesus Macaque MLF1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| MLF1-2601R-B | Recombinant Rhesus Macaque MLF1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
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| MLF1-3229H | Recombinant Human MLF1 protein, GST-tagged | E.coli | Human | GST | 1-268aa |
|
| MLF1-643HF | Recombinant Full Length Human MLF1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 268 amino acids |
|
Involved Pathway
MLF1 involved in several pathways and played different roles in them. We selected most pathways MLF1 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MLF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | HDAC1,ATM,HIST2H3A,MEF2C,LYL1,ASPSCR1,NUPR1,H3F3C,NFKBIZ,SUPT3H |
Protein Function
MLF1 has several biochemical functions, for example, DNA binding,protein binding,protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MLF1 itself. We selected most functions MLF1 had, and list some proteins which have the same functions with MLF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CHDH,TLDC2,CDK5,PRAME,SYT1,NTRK3,SFRP1,PLXNB2,EPOR,ERRFI1 |
| DNA binding | ZNF558,ZNF326,ZNF614,BARHL1A,ZNF581,BANF1,ZNF668,ZEB2,ZSCAN4D,HIST1H4F |
| protein domain specific binding | HIST2H4,CALM1,ATN1,YWHAH,TACC2,LAMP1,CHMP1A,CNOT1,VAPA,CEP68 |
Interacting Protein
MLF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MLF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MLF1.
DNAJB6;YWHAE;a8k1f4_human;a8k251_human;b2rc52_human;b4de84_human;HAX1;IRS4;GNB5;TET3;PSMD3;ZBED4;REC8;BAG2;BAG3;MOS
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