MKRN2
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Official Full Name
makorin ring finger protein 2 -
Overview
Members of the makorin family, including MKRN2, have a characteristic zinc finger composition that suggests that they;are ribonucleoproteins (Gray et al., 2001 (PubMed 11597136)). -
Synonyms
MKRN2;makorin ring finger protein 2;probable E3 ubiquitin-protein ligase makorin-2;HSPC070;RNF62;Makorin 2;Makorin2;MKRN 2;RING finger protein 62;RNF 62
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MKRN2-896H | Recombinant Human MKRN2, GST-tagged | E.coli | Human | GST | C-term-350aa | |
| MKRN2-5861C | Recombinant Chicken MKRN2 | Mammalian Cells | Chicken | His |
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| MKRN2-9445Z | Recombinant Zebrafish MKRN2 | Mammalian Cells | Zebrafish | His |
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| MKRN2-9867M | Recombinant Mouse MKRN2 Protein | Mammalian Cells | Mouse | His |
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| MKRN2-4299HCL | Recombinant Human MKRN2 293 Cell Lysate | HEK293 | Human | Non |
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| MKRN2-3603H | Recombinant Human MKRN2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Mkrn2-4086M | Recombinant Mouse Mkrn2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| MKRN2-5374H | Recombinant Human MKRN2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MKRN2-5575M | Recombinant Mouse MKRN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MKRN2-5575M-B | Recombinant Mouse MKRN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MKRN2-6345HF | Recombinant Full Length Human MKRN2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 416 amino acids |
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Involved Pathway
MKRN2 involved in several pathways and played different roles in them. We selected most pathways MKRN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MKRN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MKRN2 has several biochemical functions, for example, ligase activity,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKRN2 itself. We selected most functions MKRN2 had, and list some proteins which have the same functions with MKRN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | UBE2IB,RNF126,HECW1B,BARD1,TRIP12,UBE2G1A,RNF115,COP1,PDZRN3,TRIM56 |
| zinc ion binding | RNF122,PAPLN,SPG7,GATA2A,ZDHHC18,RECQL4,RBM14B,CA4A,LMO7B,CAR6 |
| protein binding | LYRM2,RELL2,OTX2,SARM1,ZDHHC13,DNAJC7,EFCAB4A,AGR2,ATP6AP2,ANKRD10 |
| poly(A) RNA binding | SUB1,TRMT2A,AKAP8L,PCBP2,YARS2,SSB,TNS1,P4HB,ZYX,YWHAE |
Interacting Protein
MKRN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKRN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKRN2.
e9kl35_human;UBE2D1;C1orf109;UBE2D4;HIP2;HTT;RBCK1;EZH2;TM9SF4
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References
- Schreiner, F; Gohlke, B; et al. MKRN3 Mutations in Familial Central Precocious Puberty. HORMONE RESEARCH IN PAEDIATRICS 82:122-126(2014).
- Ko, A; Shin, JY; et al. Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF. JOURNAL OF THE NATIONAL CANCER INSTITUTE 104:1660-1672(2012).
