MIXL1

  • Official Full Name

    Mix paired-like homeobox

  • Overview

    Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008]

  • Synonyms

    MIXL1;Mix paired-like homeobox;MIX;MIXL;MILD1;homeobox protein MIXL1;homeodomain protein MIX;Mix-like homeobox protein 1;mix.1 homeobox-like protein;MIX1 homeobox-like protein 1

Recombinant Proteins

  • Chicken
  • Zebrafish
  • Mouse
  • Human
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
MIXL1-6548C Recombinant Chicken MIXL1 Mammalian Cells Chicken His
MIXL1-8581Z Recombinant Zebrafish MIXL1 Mammalian Cells Zebrafish His
MIXL1-9858M Recombinant Mouse MIXL1 Protein Mammalian Cells Mouse His
MIXL1-5357H Recombinant Human MIXL1 Protein, GST-tagged Wheat Germ Human GST
MIXL1-5570M Recombinant Mouse MIXL1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MIXL1-5570M-B Recombinant Mouse MIXL1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MIXL1-6273HF Recombinant Full Length Human MIXL1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 232 amino acids

    Involved Pathway

    MIXL1 involved in several pathways and played different roles in them. We selected most pathways MIXL1 participated on our site, such as Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MIXL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adipogenesis NAMPT,DLK1,KLF7,E2F1,CTNNB1,GTF3AA,CYP26A1,CEBPA,EPAS1B,GDF10

    Protein Function

    MIXL1 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MIXL1 itself. We selected most functions MIXL1 had, and list some proteins which have the same functions with MIXL1. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II transcription factor binding TP53,DHX9,GATA6,TAL1,HCLS1,SFPI1,CHST13,TOX2,GATA1,GATA3
    RNA polymerase II core promoter proximal region sequence-specific DNA binding ZNF331,JUND,SFPI1,CEBPE,ZNF257,ZNF562,HELT,OTX2,PITX3,ZNF713
    transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding ZEB2,NFE2L1,MEOX2,HMGA1,PROP1,SUB1,CUX1,PBX3,SIX6,SPI1
    sequence-specific DNA binding FOXF1,EOMES,HOXD13A,NFYBA,ZNF394,GATA1,FOXP1A,GTF2E1,HOXC11A,FOXD1L
    transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding ARID3B,STAT3,RELA,JUN,ZFP750,MYBL2,ESRRA,GLI2,TFE3B,EPAS1
    transcriptional activator activity, RNA polymerase II transcription factor binding JUN,KLF14,GBX2,SOX10,FOXH1,NOTCH1,CREB1,KLF4,CLOCK,NR1H4
    RNA polymerase II distal enhancer sequence-specific DNA binding TAL1,CDX2,BACH2,T,POU4F1,JUN,BACH1A,NR2F6,RELA,CDX1
    protein homodimerization activity TIRAP,ASMT,DAPK3,BCL2,RPL7,FLNA,NRF1,RBM11,AMICA1,PDCD6IP
    DNA binding POLR3K,TCEB3C,AHR2,SPRTN,KAT6A,HIST1H2BN,CSDC2,RAD51D,ZHX2,ASH2L

    Interacting Protein

    MIXL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MIXL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MIXL1.

    Resources

    Research Area

    Early Endodermal Lineage Markers
    Early Mesodermal Lineage Markers
    Pluripotent Stem Cell Transcription Factors
    Ectodermal Lineage Markers
    Endodermal Lineage Markers
    Mesodermal Lineage Markers

    References

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