MINPP1
-
Official Full Name
multiple inositol-polyphosphate phosphatase 1 -
Overview
This gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway. -
Synonyms
MINPP1;multiple inositol-polyphosphate phosphatase 1;multiple inositol polyphosphate histidine phosphatase, 1;multiple inositol polyphosphate phosphatase 1;MIPP;ins(1,3,4,5)P(4) 3-phosphatase;multiple inositol polyphosphate phosphatase 2;inositol (
Recombinant Proteins
- Human
- Chicken
- Mouse
- Rat
- HEK293
- Sf9 Cells
- Mammalian Cells
- E.coli
- Yeast
- Wheat Germ
- In Vitro Cell Free System
- His
- Flag
- Non
- GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
MINPP1 involved in several pathways and played different roles in them. We selected most pathways MINPP1 participated on our site, such as Glycolysis / Gluconeogenesis,Inositol phosphate metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MINPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycolysis / Gluconeogenesis | PDHA1A,ADPGK,DLAT,GPI,ENO1,LDHBA,AKR1A1,ALDOAA,PFKL,ADH4 |
| Metabolic pathways | AMPD1,ATP5I,PAFAH2,PIK3C2B,COMTA,BAAT,ST8SIA5,NDUFB2,ALG13,PSAT1 |
| Inositol phosphate metabolism | TPI1A,MINPP1A,PI4KB,SYNJ1,MTMR2,IPPK,PLD4,PLCH1,MTMR1,ITPK1A |
Protein Function
MINPP1 has several biochemical functions, for example, acid phosphatase activity,bisphosphoglycerate 3-phosphatase activity,inositol hexakisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MINPP1 itself. We selected most functions MINPP1 had, and list some proteins which have the same functions with MINPP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphohistidine phosphatase activity | PTPRQ,CTDSPL2A,SACM1LA,PHPT1,SGPP2,SACM1L,TENC1,CTDSPL2B,LHPP,PXYLP1 |
| acid phosphatase activity | PXYLP1,ACPL2,PPIP5K2,PPIP5K1,ACP5A,PAPL,ACP1,ACP5B,ACP2,ACP6 |
Interacting Protein
MINPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MINPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MINPP1.
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