MIER1
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Official Full Name
mesoderm induction early response 1 homolog (Xenopus laevis) -
Overview
This gene encodes a protein that was first identified in Xenopus laevis by its role in a mesoderm induction early response (MIER). In human, this gene functions as a growth-factor-induced immediate early gene that encodes a transcriptional regulator. Depending on the cellular context, this gene can function as both an activator and repressor of gene transcription. Alternative splicing results in multiple isoforms; some of which contain a nuclear localization signal. -
Synonyms
MIER1;mesoderm induction early response 1 homolog (Xenopus laevis);mesoderm induction early response protein 1;hMI ER1;KIAA1610;MI ER1;ER1;Mesoderm induction early response 1;MI-ER1;hMI-ER1;RP5-944N15.1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MIER1-2948C | Recombinant Chicken MIER1 | Mammalian Cells | Chicken | His |
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| MIER1-1113HCL | Recombinant Human MIER1 cell lysate | Human | Non |
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| MIER1-5334H | Recombinant Human MIER1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MIER1-6592HF | Recombinant Full Length Human MIER1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 156 amino acids |
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Involved Pathway
MIER1 involved in several pathways and played different roles in them. We selected most pathways MIER1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MIER1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MIER1 has several biochemical functions, for example, DNA binding,protein binding,signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MIER1 itself. We selected most functions MIER1 had, and list some proteins which have the same functions with MIER1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NFKB1,UQCC2,HP,UTP11L,CDH2,PTPN1,JMJD7,UBE2Q1,FBXO18,ITGA2 |
| DNA binding | CR2,HIST1H4E,SOX19B,ZFP280D,AHRR,TRAF4,CENPA,RYBPA,BEND5,H2AFJ |
| signal transducer activity | IL10RA,TAS2R201.1,ECM1,PDCD1,TAAR11,GPR141,GPR52,STMN1,HTR5AL,CHRM5A |
Interacting Protein
MIER1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MIER1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MIER1.
HDAC1;HDAC2;EHMT2;CDYL
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References
- McCarthy, PL; Paterno, GD; et al. Protein expression pattern of human MIER1 alpha, a novel estrogen receptor binding protein. JOURNAL OF MOLECULAR HISTOLOGY 44:469-479(2013).
