MFAP5
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Official Full Name
microfibrillar associated protein 5 -
Overview
This gene encodes a 25-kD microfibril-associated glycoprotein which is rich in serine and threonine residues. It lacks a hydrophobic carboxyl terminus and proline-, glutamine-, and tyrosine-rich regions, which are characteristics of a related 31-kDa microfibril-associated glycoprotein (MFAP2). The close similarity between these two proteins is confined to a central region of 60 aa where precise alignment of 7 cysteine residues occurs. The structural differences suggest that this encoded protein has some functions that are distinct from those of MFAP2. -
Synonyms
MFAP5;microfibrillar associated protein 5;microfibrillar-associated protein 5;MAGP2;MP25;MAGP 2;MAGP-2;MFAP 5;MFAP-5;MFAP5_HUMAN;Microfibril associated glycoprotein 2;Microfibril-associated glycoprotein 2;Microfibrillar associated protein 5 precursor;microfibril-associated glycoprotein-2
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- CHO
- Mammalian cells
- HEK293
- Mammalian Cell
- Human Cell
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- His&Fc&Avi
- Fc
- GST
- His&SUMO
- Flag
Involved Pathway
MFAP5 involved in several pathways and played different roles in them. We selected most pathways MFAP5 participated on our site, such as Elastic fibre formation,Extracellular matrix organization,Molecules associated with elastic fibres, which may be useful for your reference. Also, other proteins which involved in the same pathway with MFAP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Elastic fibre formation | LOXL3,FBLN1,LOXL4,LTBP2,FBLN2,EFEMP1,FBN1,FURINB,FBN2,LTBP3 |
| Molecules associated with elastic fibres | MFAP3,MFAP1,LTBP2,LTBP3,EFEMP2,MFAP2,FBLN1,MFAP4,LTBP4,MFAP1B |
| Extracellular matrix organization | COL2A1,PCOLCE2B,CTS7,DDR2,DAG1,FN1B,BMP1B,TIMP2A,COL8A1A,ADAM9 |
| Notch signaling pathway | PSEN1,MYCBP,TUBB3,PTCRA,SNW1,RBPJB,EP300,CNTN6,NUMB,DTX4 |
Protein Function
MFAP5 has several biochemical functions, for example, extracellular matrix structural constituent. Some of the functions are cooperated with other proteins, some of the functions could acted by MFAP5 itself. We selected most functions MFAP5 had, and list some proteins which have the same functions with MFAP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| extracellular matrix structural constituent | COL11A2,EFEMP2,LAMB1,CD4,COL11A1A,COL8A2,IMPG1,COL27A1B,MATN1,COL4A3 |
Interacting Protein
MFAP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MFAP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of MFAP5.
MFAP5 Related Signal Pathway
Resources
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References
- Saekmose, SG; Schlosser, A; et al. Enzyme-Linked Immunosorbent Assay Characterization of Basal Variation and Heritability of Systemic Microfibrillar-Associated Protein 4. PLOS ONE 8:-(2013).
- Akhtar, S; Davies, JR; et al. Ultrastructural immunolocalization of alpha-elastin and keratan sulfate proteoglycan in normal and scoliotic lumbar disc. SPINE 30:1762-1769(2005).
