MEF2A
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Official Full Name
MEF2A myocyte enhancer factor 2A -
Synonyms
MEF2A;myocyte enhancer factor 2A;myocyte-specific enhancer factor 2A;serum response factor-like protein 1;MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A);mef2;ADCAD1;RSRFC4;RSRFC9
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Chicken
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- T7
- Non
- Avi
- Fc
- Flag
- DDK
- Myc
- GST
Involved Pathway
MEF2A involved in several pathways and played different roles in them. We selected most pathways MEF2A participated on our site, such as cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MEF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| cGMP-PKG signaling pathway | SLC25A6,PPP3CB,CALML3,MAPK3,ATP1B2,CALM2,IRS4,AKT2,GUCY1A3,GNAQ |
Protein Function
MEF2A has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II regulatory region sequence-specific DNA binding,RNA polymerase II transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MEF2A itself. We selected most functions MEF2A had, and list some proteins which have the same functions with MEF2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription coactivator activity | MKL1B,POU3F1,SMARCA2,WBP2,TBX20,MED12L,MYOCD,MED12,POU1F1,CITED2 |
| contributes_to protein binding | MSH6,INTS10,CRY1A,ACVR2A,MLH1,TAF10,INHA,MSH2,CPSF3L,TGFBR3 |
| protein binding | AIMP2,ZIC3,PIWIL1,SWAP70,C19orf47,ARHGAP24,HIST2H3C,CLPB,E2F8,GPR19 |
| histone deacetylase binding | RBBP4,KPNA2,NR2C1,KLF4,YWHAB,NR2E1,NRIP1,CAMTA2,CCND1,MAGEA2 |
| sequence-specific DNA binding | NR0B1,ARGFX,FOXG1,FOXL2,THRB,LHX2A,HOXB8,ZNF394,HHEX,RX3 |
| histone acetyltransferase binding | PCNA,TRIP4,HIF1A,ZBTB7A,TP53,KAT2B,EID1,ETS1,EGR1,GLI3 |
| SMAD binding | STUB1,SMURF2,SKOR1A,COL3A1,SKIL,HIPK2,EP300,YY1,COL1A2,BMPR1A |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | OVOL2,ZSCAN1,PLAGL1,NPAS4A,ATF4,SIM1A,SOX15,FOXO3,MITFA,TFAP2E |
| protein kinase binding | RPS6KA3,PIH1D1,ADCY6,FOXO3,AGTR1A,SPAG16,SYN1,DVL1,PFKFB2,CDKN2C |
Interacting Protein
MEF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MEF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of MEF2A.
Resources
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References
- Leupin, O; Kramer, I; et al. Control of the SOST bone enhancer by PTH using MEF2 transcription factors. JOURNAL OF BONE AND MINERAL RESEARCH 22:1957-1967(2007).
- Ramachandran, B; Yu, GS; et al. Nuclear respiratory factor 1 controls myocyte enhancer factor 2A transcription to provide a mechanism for coordinate expression of respiratory chain subunits. JOURNAL OF BIOLOGICAL CHEMISTRY 283:11935-11946(2008).
