MED8
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Official Full Name
mediator complex subunit 8
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MED8-11814Z | Recombinant Zebrafish MED8 | Mammalian Cells | Zebrafish | His |
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| MED8-4954C | Recombinant Chicken MED8 | Mammalian Cells | Chicken | His |
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| MED8-4378HCL | Recombinant Human MED8 293 Cell Lysate | HEK293 | Human | Non |
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| Med8-4022M | Recombinant Mouse Med8 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| MED8-4465H | Recombinant Human MED8 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MED8-6252HF | Recombinant Full Length Human MED8 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 212 amino acids |
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Involved Pathway
MED8 involved in several pathways and played different roles in them. We selected most pathways MED8 participated on our site, such as Developmental Biology,Fatty acid, triacylglycerol, and ketone body metabolism,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPARA activates gene expression | MED19,MED18,CDK19,MED20,MED9,G0S2,MED15,SREBF2,MED26,CTGF |
| Herpes simplex infection | TNFSF14,IFN-a,BLB1,SRSF5A,TNFRSF14,DAXX,TRAF5,HCFC2,PER1B,SRSF7A |
| Generic Transcription Pathway | NR6A1A,SCO1,ZNF486,ZNF726,ZFP28,ZNF19,ZNF500,TEAD3B,ZNF23,ZNF684 |
| Metabolism of lipids and lipoproteins | MED18,Agmo,MTP,SLC44A5B,ARV1,PPP1R2,AKR1C4,ELOVL1A,SLC27A5,APOEA |
| Gene Expression | ZNF705A,ZNF18,SETA,METTL1,SUGP1,ZNF155,ZNF786,ZFP1,TRMT6,ZNF74 |
| Developmental Biology | CLTC,PEA15,SCN3B,NTN1B,EPHA4A,RASGRP1,KCNQ3,EFNB2A,SPRED3,KIF4 |
| Metabolism | G0S2,SAT1B,NUDT18,AKR1C21,NFYBA,BHMT2,NDUFAF3,ESRRA,ACSM1,CYP26A1 |
| Fatty acid, triacylglycerol, and ketone body metabolism | MED29,CDK8,GLIPR1,MED25,MED31,MED21,MED18,YAP1,ELOVL1A,SREBF2 |
Protein Function
MED8 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,RNA polymerase II transcription cofactor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MED8 itself. We selected most functions MED8 had, and list some proteins which have the same functions with MED8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | GZF1,GRHL1,PITX3,MED1,JDP2,CEBPG,FOXI1,ZNF680,OVOL1,NFKB2 |
| protein binding | Mill2,CD200R2,ROR2,THEM5,ERBB4,CBX7,C14orf118,KLHL6,SCO2,RAD54L |
| RNA polymerase II transcription cofactor activity | THRAP3,MED21,MED4,MED20,MED19B,MED13A,FOXH1,MED1,PPRC1,NKX2 |
Interacting Protein
MED8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED8 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED8.
MED10;MED19;MED29;CDK19;TCEB1
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