MED31
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Official Full Name
mediator complex subunit 31 -
Overview
Mediator of RNA polymerase II transcription subunit 31 is an enzyme that in humans is encoded by the MED31 gene. -
Synonyms
MED31;mediator complex subunit 31;mediator of RNA polymerase II transcription, subunit 31 homolog (S. cerevisiae);mediator of RNA polymerase II transcription subunit 31;CGI 125;Soh1;hSOH1;mediator complex subunit SOH1;mediator of RNA polymerase II
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
MED31 involved in several pathways and played different roles in them. We selected most pathways MED31 participated on our site, such as Developmental Biology,Fatty acid, triacylglycerol, and ketone body metabolism,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPARA activates gene expression | SREBF2,APOA5,MED16,MED6,GRHL1,MED20,PLIN2,G0S2,MTF1,TIAM2 |
| Fatty acid, triacylglycerol, and ketone body metabolism | CDK19,MED21,MED8,THEM5,MED6,SLC25A1,GLIPR1,AGPAT1,MED15,MED7 |
| Developmental Biology | TDGF1,SPTBN1,DUSP5,MED18,ST8SIA2,SREBF2,CFC1,EVL,ADAM22,CRMP1 |
| Generic Transcription Pathway | NR2F6,SKILB,ZNF460,ZKSCAN5,ZNF264,ZNF485,KRBOX4,ZNF560,ZNF705A,RARAB |
| Metabolism | CYP2K16,ACSF2,GLRX,CEPT1A,MED22,GLTP,STAB2,CTH,BHMT2,TPMT.2 |
| Metabolism of lipids and lipoproteins | CPT2,ACOT9,BRSK2,CYP2R1,PTPMT1,GPAT2,SLC25A20,APOA4A,CTGF,CYP2V1 |
| Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | MED10,GLIPR1,MED20,MED23,MED18,CDK19,ANKRD1,MED7,MED21,MED16 |
| Gene Expression | ZNF225,ZNF664,CPSF4,ZNF264,ARHGEF38,ZNF254,TRMT44,ZNF124,KIAA1456,Txn1 |
Protein Function
MED31 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity,protein binding,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED31 itself. We selected most functions MED31 had, and list some proteins which have the same functions with MED31. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription cofactor activity | MED14,PPRC1,MED26,MED17,MED30,MDT-19,THRAP3,MED13B,MED19B,PPARGC1B |
| transcription coactivator activity | Ankar,TAF5L,CD3D,TFDP1A,NFKBIB,ATF2,NFE2L3,KAT6A,MYCBP,NR1I2 |
| protein binding | TUBB2B,BHLHE40,TNS4,DDC,RAB24,TMEM171,SLX4,BAG1,KCNMB4,FGF2 |
| ubiquitin protein ligase activity | MED20,BRAP,HECTD1,PARK2,HECW1B,NEDD4L,RNF217,UBR1,CDC34,MED23 |
Interacting Protein
MED31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED31 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED31.
MED10;MED19;CDK19;SELENBP1;MED26;CDK8;MED9
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