MED16

  • Official Full Name

    mediator complex subunit 16

  • Overview

    Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.

  • Synonyms

    MED16;mediator complex subunit 16;THRAP5, thyroid hormone receptor associated protein 5;mediator of RNA polymerase II transcription subunit 16;DRIP92;TRAP95;DRIP 92;MED 16;THRAP 5;Thyroid hormone receptor associated protein 5;Thyroid hormone receptor associated protein complex 95 kDa component;Trap 95;Vitamin D3 receptor interacting protein complex component;thyroid hormone receptor-associated protein 5;thyroid hormone receptor-associated protein, 95-kD subunit;vitamin D3 receptor-interacting protein complex 92 kDa component;thyroid hormone receptor-assoc;THRAP5
Cat.# Product name Source (Host) Species Tag Protein Length Price
MED16-31175TH Recombinant Human MED16, His-tagged E.coli Human His 663-751 a.a.
MED16-7886Z Recombinant Zebrafish MED16 Mammalian Cells Zebrafish His
MED16-11H Recombinant Human MED16 protein, His-tagged E.coli Human His 1-350 aa
MED16-4477H Recombinant Human MED16 Protein, GST-tagged Wheat Germ Human GST
MED16-6211HF Recombinant Full Length Human MED16 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 860 amino acids

    Involved Pathway

    MED16 involved in several pathways and played different roles in them. We selected most pathways MED16 participated on our site, such as Developmental Biology,Fatty acid, triacylglycerol, and ketone body metabolism,Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of lipids and lipoproteins CPNE3,GPAT2,YAP1,SPTLC1,ACER1,CYP4T8,MED22,CSNK1G2,FAAH2B,CYP2V1
    Metabolism ALOX5B.3,SACM1LB,ACOT10,UGT1B7,SLC4A1B,CDIPT,SLCO1B1,AKR1C6,Sult2a2,SLC6A12
    Gene Expression LBH,BARHL1,GLS2B,CD3EAP,MYBL1,SSRP1,DNAJC8,SIN3B,USP9X,ZNF167
    Generic Transcription Pathway NR1H3,ZKSCAN4,ZNF740,ZNF230,ZNF74,ZNF680,ZNF697,RARGA,RARAA,ZNF557
    Developmental Biology NRG3,MEF2AA,NRTN,GDNF,MED18,LGI1B,EFNA3B,DCC,KALRN,INSM1B
    Fatty acid, triacylglycerol, and ketone body metabolism CDK8,CYP7A1,MED9,TIAM2,MED29,ACOT9.2,MED23,MMAA,DECR1,MED15
    PPARA activates gene expression MED18,MED19,MED7,MED9,APOA5,MED10,GLIPR1,MED6,MED25,MTF1
    Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) MED31,MED10,MED23,MED26,MED15,MED6,GLIPR1,MED18,MED19,MED22

    Protein Function

    MED16 has several biochemical functions, for example, catalytic activity,protein binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED16 itself. We selected most functions MED16 had, and list some proteins which have the same functions with MED16. You can find most of the proteins on our site.

    Function Related Protein
    vitamin D receptor binding MED17,RXRA,SNW1,MED14,MED24,MED30,MED1,MED4,TAF7,THRAP3
    thyroid hormone receptor coactivator activity NCOA2,ACTN2,MED1
    catalytic activity PFKFB4L,HSD17B1,ALDOAA,GOT2A,GMPR2,ACLYA,BLM,TDH2,PPM1DB,PPTC7A
    thyroid hormone receptor binding MED30,MED13,NCOA3,HMGN3,TAF7,MED24,PRMT2,THRAP3,NR0B2,ZNHIT3
    transcription coactivator activity BIRC2,TFDP1B,APEX1,KAT2A,MYCBP,SCAND1,MED27,FUS,DYRK1B,TFAP2B
    transcription cofactor activity LDB1A,MED13,KAT2B,NFE2L1,ZNF710,CALCOCO1,SND1,ZFP710,MED12,WDR75
    receptor activity PVRL3,CD2,ERBB3B,CD33,CXCR3,Tnfrsf22,ADIPOR1A,LILRB4,GRIA2B,PVR
    protein binding STAT2,RPA2,JDP2,TOE1,MIB1,OAZ3,SEC61B,CLK2,COPB1,TET2

    Interacting Protein

    MED16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED16 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED16.

    MED10;MED19;CDK19;MED26;MED9;MED14;MED24;MED25

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