MED11
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Official Full Name
mediator complex subunit 11 -
Overview
MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008] -
Synonyms
MED11;mediator complex subunit 11;HSPC296;mediator of RNA polymerase II transcription subunit 11;mediator of RNA polymerase II transcription, subunit 11 homolog
Recombinant Proteins
- Rhesus macaque
- Zebrafish
- Mouse
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MED11-2717R | Recombinant Rhesus monkey MED11 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| MED11-7468Z | Recombinant Zebrafish MED11 | Mammalian Cells | Zebrafish | His |
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| MED11-9681M | Recombinant Mouse MED11 Protein | Mammalian Cells | Mouse | His |
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| MED11-2537R | Recombinant Rhesus Macaque MED11 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MED11-2537R-B | Recombinant Rhesus Macaque MED11 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| MED11-4480H | Recombinant Human MED11 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MED11-5442M | Recombinant Mouse MED11 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MED11-5442M-B | Recombinant Mouse MED11 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MED11-6130HF | Recombinant Full Length Human MED11 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 117 amino acids |
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| MED11-874H | Recombinant Human MED11 Protein, His-tagged | E.coli | Human | His |
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Involved Pathway
MED11 involved in several pathways and played different roles in them. We selected most pathways MED11 participated on our site, such as Mus musculus biological processes,Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with MED11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mus musculus biological processes | SUN2,KLF5,SYNE2,SYCP1,POT1A,SYCE2 |
| Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes | KLF5 |
Protein Function
MED11 has several biochemical functions, for example, RNA polymerase II transcription cofactor activity,protein binding,contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MED11 itself. We selected most functions MED11 had, and list some proteins which have the same functions with MED11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription cofactor activity | MED22,MED18,MED14,NKX2,MED20,MED13A,MED21,MED24,MED8,TP53BP1 |
| contributes_to ubiquitin protein ligase activity | FBXL6,FBXL3A,FBXL5,CUL1,FBXL7,FBXL14A,FBXL3B,CUL4A,FBXL14,UBXN6 |
| protein binding | FAM19A1,C1orf21,ARRB2,ARHGEF16,CCDC141,C22orf13,GTF2A2,CAMK2B,GTF3C3,RSL24D1 |
Interacting Protein
MED11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MED11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MED11.
MED6;MED22;MED27;MED18;Med30;Med8;MED28;MED17;MED29;Ywhae;Cdk9
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