MCM9
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Official Full Name
minichromosome maintenance complex component 9 -
Overview
The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. -
Synonyms
MCM9;minichromosome maintenance complex component 9;C6orf61, chromosome 6 open reading frame 61 , MCMDC1, minichromosome maintenance deficient domain containing 1;DNA replication licensing factor MCM9;dJ329L24.3;FLJ20170;MGC35304;C6orf61;hMCM9;MCMDC1;Mini-chromosome maintenance deficient 9;Mini-chromosome maintenance deficient domain-containing protein 1;minichromosome maintenance deficient domain containing 1;dJ329L24.1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MCM9-783H | Recombinant Human MCM9, GST-tagged | E.coli | Human | GST | 1-328aa | |
| MCM9-9642M | Recombinant Mouse MCM9 Protein | Mammalian Cells | Mouse | His |
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| MCM9-4514H | Recombinant Human MCM9 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MCM9-5416M | Recombinant Mouse MCM9 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MCM9-5416M-B | Recombinant Mouse MCM9 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MCM9-5922H | Recombinant Human MCM9 protein(1-391aa), His-tagged | E.coli | Human | His | 1-391aa |
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Involved Pathway
MCM9 involved in several pathways and played different roles in them. We selected most pathways MCM9 participated on our site, such as Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | TP53,MCM6,FGFR1OP,RAD9B,INCENP,TUBB4A,TOP2A,CSNK2A2,ESCO2,HDAC2 |
Protein Function
MCM9 has several biochemical functions, for example, ATP binding,DNA binding,helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM9 itself. We selected most functions MCM9 had, and list some proteins which have the same functions with MCM9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| helicase activity | YTHDC2,TDRD12,EIF4A1A,SMARCA4,HELLS,DDX3,EIF4A1B,DDX39,EIF4A1,ANXA1 |
| ATP binding | PANK1A,SPO11,DHX37,HIPK3,PIK3C2A,NVL,CDK18,PARS2,BCS1L,HKDC1 |
| DNA binding | EMX1,RARGA,PRKRIR,FOXC1A,VED,ZNF518A,PHTF1,CREB3,RARB,ZNF76 |
Interacting Protein
MCM9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM9 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM9.
recC;MCMBP
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