MCM3
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Official Full Name
minichromosome maintenance complex component 3 -
Overview
The minichromosome maintenance (MCM) 2-7 proteins are a family of six related proteins required for the initiation and elongation of DNA replication. MCM2-7 bind together to form the heterohexameric MCM complex that is thought to act as a replicative heli -
Synonyms
MCM3;minichromosome maintenance complex component 3;MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) , minichromosome maintenance deficient (S. cerevisiae) 3;DNA replication licensing factor MCM3;p102;RLF subunit beta;hRlf beta subunit
Recombinant Proteins
- Zebrafish
- Mouse
- Chicken
- Human
- Rhesus macaque
- Mammalian Cells
- E.coli
- Wheat Germ
- HEK293
- His
- T7
- GST
- Non
- Avi
- Fc
- Flag
- DDK
- Myc
Involved Pathway
MCM3 involved in several pathways and played different roles in them. We selected most pathways MCM3 participated on our site, such as DNA replication,Cell cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with MCM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | SYNE1,TUBGCP5,DPF1,CSNK1D,MPEG1.1,ANAPC4,GSK3AA,TMPO,MLF1IP,SYCP2 |
| DNA Replication | DBF4,GINS2,PCNA,RPA4,POLD2,MCM3L,GINS4,PRIM1,MCM2,RPA1 |
Protein Function
MCM3 has several biochemical functions, for example, ATP binding,DNA binding,DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MCM3 itself. We selected most functions MCM3 had, and list some proteins which have the same functions with MCM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZFP36L3,TET2,NKX2.5,NFAT5A,HIST2H2AC,ASXL1,MYCS,SYCP2,DNAJC2,FOXI3A |
| ATP binding | EIF4A1B,STK25A,OAS2,HYOU1,MAP4K2,PIP5K1C,ROS1,DDR2,KIF12,ATP5B |
| DNA helicase activity | IGHMBP2,FBXO18,DNA2,MCM2,RECQL5,RAD54B,MCM5,CHD8,MCM6L,WRN |
| protein binding | RCOR3,RAD9B,BTG3,C11orf65,KLK15,WDR20,HBP1,CLDN18,CANX,TPRGL |
Interacting Protein
MCM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MCM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MCM3.
MCMBP;MCM2;MCM5
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References
- Gan, N; Du, Y; et al. Increase of Mcm3 and Mcm4 expression in cervical squamous cell carcinomas. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 31:291-294(2010).
- Ren, HJ; Liu, RD; et al. Construction and use of a Trichinella spiralis phage display library to identify the interactions between parasite and host enterocytes. PARASITOLOGY RESEARCH 112:1857-1863(2013).
