MC5R
-
Official Full Name
melanocortin 5 receptor -
Overview
This gene encodes a member of the seven-pass transmembrane G protein-coupled melanocortin receptor protein family that stimulate cAMP signal transduction. The encoded protein is a receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone and is suggested to play a role in sebum generation. -
Synonyms
MC5R;melanocortin 5 receptor;melanocortin receptor 5;OTTHUMP00000162511;melanocortin-5 receptor;MC2
Recombinant Proteins
- Chicken
- Rhesus macaque
- Rat
- Human
- Sus scrofa (Pig)
- Pan troglodytes
- Bovine
- Sheep
- Mus musculus
- Mammalian Cells
- E.coli
- HEK293
- His
- His&GST
- His&Fc&Avi
Involved Pathway
MC5R involved in several pathways and played different roles in them. We selected most pathways MC5R participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MC5R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | HCRTR1,CGNRH-R,TAAR14L,GABBR2,GRIN2C,IL12,ADRB3B,MCHR1,PTGER3,CSH2 |
Protein Function
MC5R has several biochemical functions, for example, hormone binding,melanocortin receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MC5R itself. We selected most functions MC5R had, and list some proteins which have the same functions with MC5R. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ASPH,BARD1,ATP7A,NTM,XPO6,BBS7,PIWIL1,RPRM,TRAF5,TTK |
| hormone binding | UCN2,ADIPOR2,CALR,TTR,AMHR2,MTNR1A,NPR1,ADIPOR1A,ADIPOR1B,GPR30 |
| melanocortin receptor activity | MC1R,MC5RA,MC4R,MC2R,MC5RB,MC3R |
Interacting Protein
MC5R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MC5R here. Most of them are supplied by our site. Hope this information will be useful for your research of MC5R.
MRAP;MRAP2
Resources
Related Services
Related Products
References
