MARS
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Official Full Name
methionyl-tRNA synthetase -
Overview
This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules. -
Synonyms
MARS;methionyl-tRNA synthetase;methionyl-tRNA synthetase, cytoplasmic;methionine tRNA ligase 1;cytoplasmic;MetRS;Methionine tRNA ligase 1, cytoplasmic;Methionine tRNA ligase;Methionine tRNA synthetase;Methionyl tRNA synthetase;MTRNS;cytosolic methionyl-tRNA synthetase;MRS
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- His
- Myc&DDK
- GST
- His&T7
- Non
- His&Fc&Avi
- Flag
Involved Pathway
MARS involved in several pathways and played different roles in them. We selected most pathways MARS participated on our site, such as Selenocompound metabolism,Aminoacyl-tRNA biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Selenocompound metabolism | INMT,TXNRD3,CCBL2,TRR1,PAPSS2B,MTR,PSTK,SCLY,TXNRD1,SEPHS1 |
| Aminoacyl-tRNA biosynthesis | QARS,SARS,FARS2,CARS,YARS,FARSB,LARS,GATC,NARS,DARS |
Protein Function
MARS has several biochemical functions, for example, ATP binding,methionine-tRNA ligase activity,tRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARS itself. We selected most functions MARS had, and list some proteins which have the same functions with MARS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tRNA binding | YARS2,PSTK,AARS,PTCD1,ALKBH8,THG1L,FDXACB1,METTL1,TRMT1,CTU1 |
| methionine-tRNA ligase activity | MARS2 |
| ATP binding | DNAH6,UBA3,LIG1,KIF7,EGFR,FGFR4,MCM2,NADK2,MYH13,UBE2NB |
Interacting Protein
MARS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARS here. Most of them are supplied by our site. Hope this information will be useful for your research of MARS.
MYC;gag;7242199;GIPC1;TFE3;MCC;HLA-B;NFKB2;MDM2;RELA;MAP3K1;ILK;Hacd3;MAP3K3;PPP5C;BRF2;WRAP73;TNFRSF10D
Resources
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References
- Blanco, Y; Quesada, A; et al. CYANOCHIP: An Antibody Microarray for High-Taxonomical-Resolution Cyanobacterial Monitoring. ENVIRONMENTAL SCIENCE & TECHNOLOGY 49:1611-1620(2015).
- Eggert-Kruse, W; Batschulat, K; et al. Male immunity to the chlamydial 60 kDa heat shock protein (HSP 60) - associated with semen quality?. ANDROLOGIA 47:66-76(2015).
