MARK1
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Official Full Name
MAP/microtubule affinity-regulating kinase 1 -
Overview
May play a role in cytoskeletal stability. -
Synonyms
MARK1;MAP/microtubule affinity-regulating kinase 1;serine/threonine-protein kinase MARK1;MARK;PAR1 homolog c;Par1c;Par-1c;KIAA1477;MGC126512;MGC126513
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Sf9 Cells
- Insect Cells
- Mammalian Cells
- HEK293
- E.coli
- Sf21 Cells
- GST
- His
- Non
- Avi&Fc&His
Involved Pathway
MARK1 involved in several pathways and played different roles in them. We selected most pathways MARK1 participated on our site, such as Regulation of Microtubule Cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Microtubule Cytoskeleton | CFL2,MAP1B,MARK2,TESK2,DPYSL2,TPPP |
Protein Function
MARK1 has several biochemical functions, for example, ATP binding,magnesium ion binding,phosphatidic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARK1 itself. We selected most functions MARK1 had, and list some proteins which have the same functions with MARK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activity | PIK3CG,CSNK1G2B,ERN2,STK32A,AKT3A,VRK3,TAOK2,PSKH2,CSNK2A1,PRKAA2 |
| phosphatidylserine binding | TRIM72,THBS1,CD300A,SCARB1,MFGE8,AXL,SYTL2,RS1,GAS6,GAP43 |
| magnesium ion binding | RRAGC,MAP3K8,NT5C3A,TDP2,NEK6,PPA2,SRR,PPA1,MAP3K6,NT5C1B |
| phosphatidic acid binding | RAPGEF6,MICALL1,NRGN,PLCD1,COMMD1,JPH2,SESTD1,MAPKAP1,PACSIN2,UQCC3 |
| phosphatidylinositol-4,5-bisphosphate binding | FAM123A,PFN1,ACTN2,CHMP3,CCDC167,JPH2,ALOX15,SESTD1,SNX20,TWF1 |
| ATP binding | IKBKAP,DDX27,CDK13,EPHA2A,ABCF1,IARS,DHX38,KSR2,RUNX2B,PTK6 |
| tau-protein kinase activity | PHKG1,MARK2,MARK4,CDK5,PHKG2,GSK3B,GSK3A,CSNK1D,PRKAA1 |
Interacting Protein
MARK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARK1.
YWHAZ;MAPT;MAPT;SFN;YWHAG;MARK2;USP21;GJA5;imatinib;midostaurin;npm_alk;YWHAB;YWHAE;YWHAH;Cdc20
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