MARCKSL1
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Official Full Name
MARCKS-like 1 -
Overview
Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) is a major PKC substrate expressed in many cell types. MARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic, and mitogenesis (1). PKC phosphorylates Ser159, 163, -
Synonyms
MARCKSL1;MARCKS-like 1;MARCKS-related protein;macMARCKS;mac-MARCKS;brain protein F52;MARCKS-like protein 1;myristoylated alanine-rich C kinase substrate;macrophage myristoylated alanine-rich C kinase substrate;F52;Mlp;MGC93399
Recombinant Proteins
- Rhesus macaque
- Rat
- Chicken
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&GST
- His&Fc&Avi
- GST
Involved Pathway
MARCKSL1 involved in several pathways and played different roles in them. We selected most pathways MARCKSL1 participated on our site, such as Fc gamma R-mediated phagocytosis,Leishmaniasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARCKSL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fc gamma R-mediated phagocytosis | CFL2,PIK3R3,PRKCB,GAB2,PPAP2C,HCK,PIP5K1C,PRKCD,LIMK1,GSN |
| Leishmaniasis | MYD88,NCF2,TGFB2,H2-AA,TAB2,IL4,HLA-DPB1,ITGB2L,STAT1,CYBA |
Protein Function
MARCKSL1 has several biochemical functions, for example, actin binding,calmodulin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARCKSL1 itself. We selected most functions MARCKSL1 had, and list some proteins which have the same functions with MARCKSL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calmodulin binding | CALD1B,REM1,ITPKC,KCNN1,TRPV6,CAMK2B1,MYH13,SNTA1,MYO1A,CALD1 |
| protein binding | ZNF238,TJP1,FFAR2,BCAP31,LAMP2,BBS12,KRIT1,IRAK1,RNF2,MAD2L2 |
| actin binding | MYO5B,KCNMA1,ESPN,CFL1,MYH11A,SPTBN1,PDLIM5,MSRB1A,FGD4,MYO1H |
Interacting Protein
MARCKSL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARCKSL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARCKSL1.
LOXL2;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;ssdna_dtdg;PAX6;MAPK14
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