MARCH4
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Official Full Name
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase -
Synonyms
MARCH4;membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase;29269;ENSG00000144583;RNF174;MARCH-IV;2q35;MGC104908;E3 ubiquitin-protein ligase MARCH4;E3 ubiquitin-protein ligase MARCH4;RING finger protein 174;membrane-associated RING-CH protein IV;membrane-associated RING finger protein 4
Recombinant Proteins
- Rhesus macaque
- Zebrafish
- Mouse
- Human
- zebrafish
- Mus musculus
- Mammalian Cells
- HEK293
- E.coli
- His
- His&Fc&Avi
Involved Pathway
MARCH4 involved in several pathways and played different roles in them. We selected most pathways MARCH4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MARCH4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
MARCH4 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MARCH4 itself. We selected most functions MARCH4 had, and list some proteins which have the same functions with MARCH4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| tubulin-glycine ligase activity | MARCH6,ITCHA,TRIM50,TMEM129,RNF144AB,ZNRF2B,LTN1,G2E3,NEURL3,HECW2 |
| coenzyme F420-0 gamma-glutamyl ligase activity | TMEM129,HERC2,MARCH6,MARCH9,SHRPRBCK1R,RNF149,ITCHA,UBE2IB,RNF180,MARCH11 |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | ZNRF3,RNF187,ZNRF2B,SIAH2L,MUL1A,HECW2,RNF144AB,TRIM71,G2E3,DTX1 |
| protein-glutamic acid ligase activity | ARIH1L,UBE2IB,G2E3,ZNRF3,HERC2,MARCH5L,RC3H2,MYLIPB,TMEM129,SHRPRBCK1R |
| protein-glycine ligase activity, initiating | RFWD2,ITCHA,TRIM50,HERC2,SHRPRBCK1R,UBR1,ARIH1L,MARCH6,ZNRF2B,RNF149 |
| zinc ion binding | USP22,RERE,NR5A1A,XAF1,ZNFL1,QPCT,SHARPIN,CXXC1A,LONRF2,ZNF75D |
| metal ion binding | TCN2,MGAT4C,ZNF485,IMPDH1,LIMS2,ZBTB8A,ZNF571,TRIM26,METAP1D,ZNF174 |
| coenzyme F420-2 alpha-glutamyl ligase activity | ARIH1L,RNF144AB,UBE2IA,MARCH11,MARCH5L,NEURL1B,MYLIPB,SIAH1A,ZNRF3,RNF144AA |
| ubiquitin-protein transferase activity | LNX1,TRIM24,RNF25,FBXW2,FBXO22,UBE2B,FBXO7,ANAPC4,NLRC4,UBE2T |
Interacting Protein
MARCH4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARCH4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARCH4.
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