MAN1A1
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Official Full Name
mannosidase, alpha, class 1A, member 1 -
Overview
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the removal of 3 distinct mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. -
Synonyms
MAN1A1;mannosidase, alpha, class 1A, member 1;mannosyl-oligosaccharide 1,2-alpha-mannosidase IA;2-alpha-mannosidase IA;2-mannosidase IA;Alpha 1,2 mannosidase IA;Alpha-1;EC 3.2.1.113;HUMM3;HUMM9;MA1A1_HUMAN;Man(9) alpha mannosidase;Man(9)-alpha-mannosidase;MAN9;Man9 mannosidase;Man9-mannosidase;Mannosidase alpha class 1A member 1;Mannosyl-oligosaccharide 1;Mannosyl-oligosaccharide 1,2 alpha mannosidase IA;OTTHUMP00000017107;Processing alpha 1,2 mannosidase IA;Processing alpha-1;alpha-1,2-mannosidase IA;processing alpha-1,2-mannosidase IA
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MAN1A1-27144TH | Recombinant Human MAN1A1 | Wheat Germ | Human | Non | 90 amino acids |
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| MAN1A1-1049HCL | Recombinant Human MAN1A1 cell lysate | Human | Non |
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| MAN1A1-1549H | Recombinant Human MAN1A1 protein, His & GST-tagged | E.coli | Human | His&GST | Ile322~Glu653 |
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| RFL10734SF | Recombinant Full Length Pig Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ia(Man1A1) Protein, His-Tagged | E.coli | Sus scrofa (Pig) | His | Full L. Full Length (1-659) |
|
| RFL32465MF | Recombinant Full Length Mouse Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ia(Man1A1) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-655) |
|
| RFL35704HF | Recombinant Full Length Human Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase Ia(Man1A1) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-653) |
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Involved Pathway
MAN1A1 involved in several pathways and played different roles in them. We selected most pathways MAN1A1 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways,Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAN1A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | AMFR,EIF2AK2,SEC61G,DNAJC1,XBP1,HSPA8,HSP70,MAPK9,DNAJC3A,SEC31B |
| N-Glycan biosynthesis | MOGS,MGAT4C,ALG12,DPM3,FUT8,STT3A,MGAT1B,ALG6,MGAT5B,MGAT4A |
| Metabolic pathways | PKLR,ENPP1,HADH,CES1C,PLA2G12A,PIGK,PANK2,CMPK2,ARSB,ISYNA1 |
Protein Function
MAN1A1 has several biochemical functions, for example, calcium ion binding,mannosidase activity,mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAN1A1 itself. We selected most functions MAN1A1 had, and list some proteins which have the same functions with MAN1A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | MMP25,CAPN2L,BGLAP2,PCDH2AB7,CANT1B,GCH1,SWAP70B,RASGRP1,S100A14,PLCD1B |
| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | MAN1C1,EDEM2,MAN1A,EDEM1,MAN1B1,MAN1A2 |
| mannosidase activity | EDEM1,MAN1A |
Interacting Protein
MAN1A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAN1A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAN1A1.
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