Mammaglobin
-
Official Full Name
-
Overview
Mammaglobin is a 93 amino acid protein with homology to other secretoglobin-uteroglobin family members that was originally identified in studies of differentially expressed cDNAs from breast carcinoma cell lines. Mammaglobin expression has also been reported in a series of malignant and nonmalignant tissues derived from the female genital tract by RT-PCR. Expression of the mammaglobin gene and protein have been demonstrated in neoplastic breast tissues and in a subset of normal breast epithelial cells within the acini of type I and type II lobules and within the columnar cells of terminal ducts. Mammaglobin expression has been found in well, moderately, and poorly differentiated invasive ductal carcinomas by IHC and in metastatic and occult breast carcinoma by RT-PCR. Mammaglobin expression is highly restricted to breast tissue and not detected in the majority of normal tissue types evaluated, with the exception of skin. -
Synonyms
Mammaglobin;Mammaglobin 1;Mammaglobin-1;Mammaglobin-A;MGB1;Scgb2a2;Secretoglobin family 2A member 2;SG2A2;SG2A2_HUMAN;UGB2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|
Involved Pathway
Mammaglobin involved in several pathways and played different roles in them. We selected most pathways Mammaglobin participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Mammaglobin were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Mammaglobin has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Mammaglobin itself. We selected most functions Mammaglobin had, and list some proteins which have the same functions with Mammaglobin. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
Mammaglobin has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mammaglobin here. Most of them are supplied by our site. Hope this information will be useful for your research of Mammaglobin.
Resources
Related Services
Related Products
References
- Wendroth, SM; Mentrikoski, MJ; et al. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. ANNALS OF DIAGNOSTIC PATHOLOGY 19:6-9(2015).
- Krings, G; Nystrom, M; et al. Diagnostic utility and sensitivities of GATA3 antibodies in triple-negative breast cancer. HUMAN PATHOLOGY 45:2225-2232(2014).
