MAGEB1
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Official Full Name
melanoma antigen family B, 1 -
Overview
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. -
Synonyms
MAGEB1;melanoma antigen family B, 1;melanoma-associated antigen B1;cancer/testis antigen family 3;member 1;CT3.1;DAM10;DSS/AHC critical interval MAGE superfamily 10;MAGE Xp;MAGEL1;MGC9322;Cancer/testis antigen 3.1;DSS AHC critical interval MAGE superfamily 10;MAGE B1 antigen;MAGEXP antigen;Melanoma associated antigen B1;MAGE-B1 antigen;MAGE-XP antigen;cancer/testis antigen family 3, member 1;DSS-AHC critical interval MAGE superfamily 10;MAGE-Xp
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
- His&Myc
Involved Pathway
MAGEB1 involved in several pathways and played different roles in them. We selected most pathways MAGEB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MAGEB1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEB1 itself. We selected most functions MAGEB1 had, and list some proteins which have the same functions with MAGEB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
MAGEB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEB1.
SRPK2;SRPK1
Resources
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References
- Melero, I; Hirschhorn-Cymerman, D; et al. Agonist Antibodies to TNFR Molecules That Costimulate T and NK Cells. CLINICAL CANCER RESEARCH 19:1044-1053(2013).
- Tjiu, JW; Lin, PJ; et al. SLURP1 mutation-impaired T-cell activation in a family with mal de Meleda. BRITISH JOURNAL OF DERMATOLOGY 164:47-53(2011).
