MAGEA6
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Official Full Name
melanoma antigen family A, 6 -
Overview
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene. -
Synonyms
MAGEA6;melanoma antigen family A, 6;MAGE6;melanoma-associated antigen 6;cancer/testis antigen family 1;member 6;CT1.6;MAGE 6 antigen;melanoma antigen family A 6;melanoma associated antigen 6;Cancer/testis antigen 1.6;MAGA6_HUMAN;MAGE 3b;MAGE-6 antigen;MAGE3B;MAGE3B antigen;OTTHUMP00000024223;OTTHUMP00000024224;OTTHUMP00000205538;cancer/testis antigen family 1, member 6;MAGE-3b
Recombinant Proteins
- Human
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- His&T7
- Non
- His
- His&Myc
- His&Fc&Avi
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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MAGEA6-232H | Recombinant Human MAGEA6 protein, T7/His-tagged | E.coli | Human | His&T7 | 2-314 a.a. |
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MAGEA6-30166TH | Recombinant Human MAGEA6 | Wheat Germ | Human | Non | 314 amino acids |
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MAGEA6-403H | Recombinant Human MAGEA6 | Mammalian Cells | Human | His |
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MAGEA6-6788H | Recombinant Human Melanoma Antigen Family A, 6, His-tagged | E.coli | Human | His |
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MAGEA6-4551HCL | Recombinant Human MAGEA6 293 Cell Lysate | HEK293 | Human | Non |
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MAGEA6-296HF | Recombinant Full Length Human MAGEA6 Protein | In Vitro Cell Free System | Human | Full L. 314 amino acids |
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MAGEA6-3200H | Recombinant Human MAGEA6 protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-314aa |
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MAGEA6-3419H | Recombinant Human MAGEA6 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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MAGEA6-3419H-B | Recombinant Human MAGEA6 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
MAGEA6 involved in several pathways and played different roles in them. We selected most pathways MAGEA6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MAGEA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
MAGEA6 has several biochemical functions, for example, molecular_function,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA6 itself. We selected most functions MAGEA6 had, and list some proteins which have the same functions with MAGEA6. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | LRRC29,UPP2,APOBEC2B,DSCC1,TXLNG,DNAJA3,Ccl27a,GTF2F1,DZIP1,SP1 |
molecular_function | RPL41,BNIP4,CDCP1A,BEX6,CCDC106A,GM996,GPR25,TMEM232,HAUS8,EFCAB5 |
Interacting Protein
MAGEA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA6.
TXNDC9;ACOT7;BET1;NCK2;ATP6V1G1;TULP3;SNX4
Resources
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References
- Lee, OJ; Son, SM; et al. CEACAM6 as detected by the AP11 antibody is a marker notable for mucin-producing adenocarcinomas. VIRCHOWS ARCHIV 466:151-159(2015).
- Zhang, QM; He, SJ; et al. Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3918-3927(2014).