LRRK1

  • Official Full Name

    leucine-rich repeat kinase 1

  • Overview

    Leucine-rich repeat serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the LRRK1 gene.

  • Synonyms

    LRRK1;leucine-rich repeat kinase 1;leucine-rich repeat serine/threonine-protein kinase 1;FLJ23119;KIAA1790;RIPK6;Roco1;Leucine rich repeat serine/threonine protein kinase 1;LRRK 1

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • Non
  • GST
  • Avi&Fc&His
Cat.# Product name Source (Host) Species Tag Protein Length Price
LRRK1-647H Recombinant Human LRRK1, His-tagged E.coli Human His C-term-357aa
LRRK1-9309M Recombinant Mouse LRRK1 Protein Mammalian Cells Mouse His
LRRK1-1035HCL Recombinant Human LRRK1 cell lysate Human Non
LRRK1-4638H Recombinant Human LRRK1 Protein, GST-tagged Wheat Germ Human GST
LRRK1-5212M Recombinant Mouse LRRK1 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
LRRK1-5212M-B Recombinant Mouse LRRK1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
LRRK1-6078HF Recombinant Full Length Human LRRK1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 261 amino acids

    Involved Pathway

    LRRK1 involved in several pathways and played different roles in them. We selected most pathways LRRK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LRRK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    LRRK1 has several biochemical functions, for example, ATP binding,GTP binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRRK1 itself. We selected most functions LRRK1 had, and list some proteins which have the same functions with LRRK1. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding RBM10,CBY1,KCNIP2,TRIM39,CTSC,ASS1,TP53,LYZ1,LCP1,PKD2L1
    protein serine/threonine kinase activity CDC42BPG,SMOK2B,RIPK1,PAK1,VRK2,CASK,VPRBP,STK32C,MARK4,MAP4K2
    ATP binding CHUK,MERTK,MYH1,TRAP1,TRIT1,CAMK1GA,RUNX2,PYGL,TESK1,CMPK2
    protein binding SLC22A7,ANKRD10,HER11,RNF216,PPP2R3C,SMAD6,DOLK,GAB3,PIAS2,GTF2I
    metal ion binding COX5B,ZNF280D,FAM20B,ZNF643,CSH1,ZDHHC18B,U2AF1L4,POLL,PDE3A,FHL2B
    GTP binding TUBA8L3,RAB27B,URGCP,RAB11AL,SEPT6,SRPRB,TUBB2B,GUCY2E,TUBA1B,RAB40AL

    Interacting Protein

    LRRK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRK1.

    BAG5;ABL1;LRRK2;EGFR;HSPA8;GRB2

    Resources

    References

    • Biskup, S; Moore, DJ; et al. Dynamic and redundant regulation of LRRK2 and LRRK1 expression. BMC NEUROSCIENCE 8:-(2007).

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