LRRFIP1
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Official Full Name
leucine rich repeat (in FLII) interacting protein 1 -
Overview
Leucine-rich repeat flightless-interacting protein 1 is a protein that in humans is encoded by the LRRFIP1 gene. -
Synonyms
LRRFIP1;leucine rich repeat (in FLII) interacting protein 1;leucine-rich repeat flightless-interacting protein 1;FLAP 1;FLIIAP1;GC binding factor 2;GCF 2;HUFI 1;TRIP;GC-binding factor 2;NEDD8-conjugating enzyme;TAR RNA-interacting protein;LRR
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- Flag
- His&Strep
- Myc&DDK
- His&Fc&Avi
Involved Pathway
LRRFIP1 involved in several pathways and played different roles in them. We selected most pathways LRRFIP1 participated on our site, such as Cytosolic sensors of pathogen-associated DNA,Disease,Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LRRFIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| FGFR1 mutant receptor activation | FGFR1OP2,CUX1,TRIM24,MYO18A,FGFR1OP,CPSF6 |
| Immune System | WIPF3,TNRC5,DEFB103A,UBR1,ASB4,DHX9,RACGAP1,ASB2,PCBP2,CFHL3 |
| Diseases of signal transduction | TNKS,HEYL,TRAT1,TTR,FGFR1OP,MIB1,RLBP1,KREMEN2,STRA6,FGFR1OP2 |
| Disease | FGFR1OP2,RCC1,AP2A1,CTBP2,EPM2A,AP1S1,KREMEN2,KPNA3,KREMEN1,OS9 |
| Cytosolic sensors of pathogen-associated DNA | NLRP4C,RIPK3,DHX9,S100B,POLR3G,NLRP4E,APPA,POLR3C,NLRP4B,S100A12 |
| Signaling by FGFR in disease | MYO18A,CPSF6,TRIM24,CUX1,FGFR1OP2 |
| Innate Immune System | POLR3G,MAP3K8,CASP2,LY86,PPAPDC1B,ACTR2B,DUSP3B,FCN2,RNF135,S100B |
Protein Function
LRRFIP1 has several biochemical functions, for example, DNA binding,double-stranded RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LRRFIP1 itself. We selected most functions LRRFIP1 had, and list some proteins which have the same functions with LRRFIP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| double-stranded RNA binding | TUBB4B,MSN,YRDC,EIF2C3,RNASEN,DICER1,AGO2,TARBP2,MBNL1,OAS3 |
| protein homodimerization activity | CADM1A,RIPK2,DCK,CD8A,CISD2,ASGR1,TYMS,ABCD2,GOT2,TRIM37 |
| DNA binding | HIST1H2AG,TLR8,KLF12,HOXA13B,KLF9,ZNF454,PPARGC1A,PPARAA,IRF3,ETV5 |
| protein binding | SYNJ2,NFE2L2,NFYC,JIP1,CRYBA1,PSMC6,CYFIP1,TRIM26,SIRT4,DNAI1 |
Interacting Protein
LRRFIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LRRFIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LRRFIP1.
FLII;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;ESR1
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