LIPF
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Official Full Name
lipase, gastric -
Overview
This gene encodes gastric lipase, an enzyme involved in the digestion of dietary triglycerides in the gastrointestinal tract, and responsible for 30% of fat digestion processes occurring in human. It is secreted by gastric chief cells in the fundic mucosa of the stomach, and it hydrolyzes the ester bonds of triglycerides under acidic pH conditions. The gene is a member of a conserved gene family of lipases that play distinct roles in neutral lipid metabolism. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
LIPF;lipase, gastric;gastric triacylglycerol lipase;HGL;HLAL;gastric lipase;GL;OTTHUMP00000020038;OTTHUMP00000020039
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- HEK293
- Insect Cells
- Mammalian Cells
- E.coli
- Human Cells
- Wheat Germ
- In Vitro Cell Free System
- Myc&DDK
- His
- His&GST
- Non
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LIPE-8393H | Recombinant Human LIPF Protein, Myc/DDK-tagged | HEK293 | Human | Myc&DDK |
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| LIPF-101H | Recombinant Human LIPF, His-tagged | Insect Cells | Human | His | 1-398 a.a. |
|
| LIPF-12578Z | Recombinant Zebrafish LIPF | Mammalian Cells | Zebrafish | His |
|
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| LIPF-128H | Recombinant Human LIPF, His-tagged | HEK293 | Human | His | 20-398 a.a. |
|
| LIPF-292H | Recombinant Human LIPF, His-tagged | Insect Cells | Human | His | Met1-Lys398 |
|
| LIPF-3418R | Recombinant Rat LIPF Protein | Mammalian Cells | Rat | His |
|
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| LIPF-7939H | Recombinant Human LIPF protein, His & GST-tagged | E.coli | Human | His&GST | Leu20~Lys398 |
|
| LIPF-9129M | Recombinant Mouse LIPF Protein | Mammalian Cells | Mouse | His |
|
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| LIPF-001HCL | Recombinant Human LIPF cell lysate | Human Cells | Human | Non |
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| LIPF-05H | Recombinant Human LIPF Protein, GST-tagged | Wheat Germ | Human | GST | 299-398 |
|
| LIPF-06H | Recombinant Human LIPF Protein, GST-tagged | Wheat Germ | Human | GST | 1-398 |
|
| LIPF-3074R | Recombinant Rat LIPF Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| LIPF-3074R-B | Recombinant Rat LIPF Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| LIPF-5099M | Recombinant Mouse LIPF Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| LIPF-5099M-B | Recombinant Mouse LIPF Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| LIPF-5218H | Recombinant Human LIPF Protein (Leu20-Lys398), C-His tagged | Mammalian Cells | Human | His | Leu20-Lys398 |
|
| LIPF-5220H | Recombinant Human LIPF Protein (Leu20-Lys398), N-GST tagged | E.coli | Human | GST | Leu20-Lys398 |
|
| LIPF-6863HF | Recombinant Full Length Human LIPF Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 398 amino acids |
|
Involved Pathway
LIPF involved in several pathways and played different roles in them. We selected most pathways LIPF participated on our site, such as Glycerolipid metabolism,Metabolic pathways,Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with LIPF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerolipid metabolism | glpK,ALDH7A1,DGKAA,GK2,PPAP2CB,GK,LYCAT,GPAT2,MOGAT3,LPIN3 |
| Fat digestion and absorption | PLA2G2F,PLA2G12B,DGAT2,SLC27A4,MTTP,APOB,FABP2,PLA2G5,ABCA1,ACAT2 |
| Metabolic pathways | COX7B2,ADH7,ACSL1B,CERS2A,glpK,AGPAT3,GLS,DHDPSL,PHOSPHO2,INPP4A |
Protein Function
LIPF has several biochemical functions, for example, lipid binding,malate dehydrogenase activity,triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LIPF itself. We selected most functions LIPF had, and list some proteins which have the same functions with LIPF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| triglyceride lipase activity | PNPLA4,AADAC,LIPC,CES3,PNLIPRP3,PNPLA3,LPL,Cel,PNLIPRP1,CEL.1 |
| malate dehydrogenase activity | MDH1B,MDH1AA |
| lipid binding | CADPS,FER,SH3GL1,DOK7,PTGS2,APOA4A,ALOX8,O3far1,STARD10,APOA4B.1 |
Interacting Protein
LIPF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LIPF here. Most of them are supplied by our site. Hope this information will be useful for your research of LIPF.
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References
- Luo, C; Zhu, YJ; et al. Carbonized Polyacrylonitrile-Stabilized SeSx Cathodes for Long Cycle Life and High Power Density Lithium Ion Batteries. ADVANCED FUNCTIONAL MATERIALS 24:4082-4089(2014).
- Voigt, N; Stein, J; et al. The role of lipolysis in human orosensory fat perception. JOURNAL OF LIPID RESEARCH 55:870-882(2014).
