LGALS2
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Official Full Name
lectin, galactoside-binding, soluble, 2 -
Overview
The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. -
Synonyms
LGALS2;lectin, galactoside-binding, soluble, 2;galectin-2;galectin 2;HL14;gal-2;S-Lac lectin 2;lactose-binding lectin 2;beta-galactoside-binding lectin L-14-II;MGC75071;AI324147;2200008F12Rik
Recombinant Proteins
- Human
- Mouse
- Rat
- Pig
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Avi&Fc&His
- GST
- DDK&Myc
Involved Pathway
LGALS2 involved in several pathways and played different roles in them. We selected most pathways LGALS2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
LGALS2 has several biochemical functions, for example, carbohydrate binding,galactoside binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS2 itself. We selected most functions LGALS2 had, and list some proteins which have the same functions with LGALS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| carbohydrate binding | ASGR1,SIGLEC9,LMAN1L,CLEC11A,CD34,HBL4,CALR,BCAN,CLEC14A,MLEC |
| galactoside binding | GLA,LGALS3L,LGALS1L1,GLB1,LGALS9L1,LGALS2A,LGALS2B |
| protein binding | MAP3K3,CDK9,CREB3L3,ASPSCR1,CDAN1,DSTN,ENTPD3,FAM76B,IL33,KLHL2 |
Interacting Protein
LGALS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS2.
SDCBP;SDCBP2;LTA;TUBA1A
Resources
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References
- Garcia, E; Sanchis, JB; et al. THE IMPORTANCE OF IMMUNOREGULATORY GENES IN NON SMALL CELL LUNG CANCER. JOURNAL OF THORACIC ONCOLOGY 8:S756-S756(2013).
- van der Laan, AM; Schirmer, SH; et al. Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis. EUROPEAN HEART JOURNAL 33:1076-1084(2012).
