LGALS13
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Official Full Name
lectin, galactoside-binding, soluble, 13 -
Overview
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene has lysophospholipase activity. It is composed of two identical subunits which are held together by disulfide bonds. This protein has structural similarity to several members of the beta-galactoside-binding S-type lectin family. -
Synonyms
LGALS13;lectin, galactoside-binding, soluble, 13;galactoside-binding soluble lectin 13;galectin 13;PLAC8;PP13;gal-13;galectin-13;placental protein 13;placental tissue protein 13;beta-galactoside-binding lectin;GAL13
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| LGALS13-2493H | Recombinant human LGALS13, His-tagged | E.coli | Human | His |
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| LGALS13-458H | Recombinant Human Lectin, Galactoside-Binding, Soluble, 13 | Human | Human | Non |
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| LGALS13-4768HCL | Recombinant Human LGALS13 293 Cell Lysate | HEK293 | Human | Non |
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| LGALS13-133H | Recombinant Human LGALS13 Protein (Ser2-Asn139), N-His tagged, Animal-free, Carrier-free | E.coli | Human | His | Ser2-Asn139 |
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| LGALS13-4220H | Recombinant Human LGALS13 Protein (Met1-Asn139), N-GST tagged | E.coli | Human | GST | Met1-Asn139 |
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| LGALS13-6270H | Recombinant Human LGALS13 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
LGALS13 involved in several pathways and played different roles in them. We selected most pathways LGALS13 participated on our site, such as Integrated Breast Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with LGALS13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Integrated Breast Cancer Pathway | MYT1,GDI1,RPP38,ANXA1,EDAR,CYP19A1,USP16,NOXA1,DCAKD,DHTKD1 |
Protein Function
LGALS13 has several biochemical functions, for example, carbohydrate binding,lysophospholipase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LGALS13 itself. We selected most functions LGALS13 had, and list some proteins which have the same functions with LGALS13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| lysophospholipase activity | ASPG,PLA2G15,PLA2G4F,PLA2G4AA,PNPLA6,PLA2G4B,PNPLA7,PNPLA7A,ENPP2,LYPLA1 |
| carbohydrate binding | MAG,CLEC4A2,SIGLEC6,GALNT7,WBSCR17,FBXO2,KLRD1,DGCR2,REG1A,Chil3 |
| protein binding | RPH3AL,CCND1,CUL3,RERE,RAB35,KIF1C,RARRES2,HDDC2,KLB,FBXW8 |
Interacting Protein
LGALS13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LGALS13 here. Most of them are supplied by our site. Hope this information will be useful for your research of LGALS13.
Hoxa1;NUFIP2;HOXA1;PACSIN3;CREB5
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References
- Than, NG; Romero, R; et al. Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia. PLACENTA 35:855-865(2014).
- Seabrook, JL; Cantlon, JD; et al. Role of LIN28A in Mouse and Human Trophoblast Cell Differentiation. BIOLOGY OF REPRODUCTION 89:-(2013).
