KLK14
-
Official Full Name
kallikrein-related peptidase 14 -
Overview
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined. [provided by RefSeq, Jul 2008] -
Synonyms
KLK14;kallikrein-related peptidase 14;KLK-L6;kallikrein-14;hK14;kallikrein 14;kallikrein-like protein 6
Recombinant Proteins
- Human
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Yeast
- His
- His&GST
- Non
- His&SUMO
- His&Fc&Avi
Involved Pathway
KLK14 involved in several pathways and played different roles in them. We selected most pathways KLK14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KLK14 has several biochemical functions, for example, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK14 itself. We selected most functions KLK14 had, and list some proteins which have the same functions with KLK14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase activity | TPSAB1,ST14B,HTRA1B,ST14A,PRSS27,ELA2,TMPRSS4,FAP,GZMH,F9 |
Interacting Protein
KLK14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK14 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK14.
Resources
Related Services
Related Products
References
- Gratio, V; Loriot, C; et al. Kallikrein-Related Peptidase 14 Acts on Proteinase-Activated Receptor 2 to Induce Signaling Pathway in Colon Cancer Cells. AMERICAN JOURNAL OF PATHOLOGY 179:2625-2636(2011).
- Ricciardelli, C; Bianco-Miotto, T; et al. Comparative Biomarker Expression and RNA Integrity in Biospecimens Derived from Radical Retropubic and Robot-Assisted Laparoscopic Prostatectomies. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 19:1755-1765(2010).
