KIF21A
-
Official Full Name
kinesin family member 21A -
Overview
This gene encodes a member of the KIF4 subfamily of kinesin-like motor proteins. The encoded protein is characterized by an N-terminal motor domain a coiled-coil stalk domain and a C-terminal WD-40 repeat domain. This protein may be involved in microtubule dependent transport. Mutations in this gene are the cause of congenital fibrosis of extraocular muscles-1. Alternate splicing results in multiple transcript variants. -
Synonyms
KIF21A;kinesin family member 21A;kinesin-like protein KIF21A;N-5 kinesin;AI850764;mKIAA1708
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KIF21A-3717H | Recombinant Human KIF21A protein, GST-tagged | E.coli | Human | GST | 1125-1230 aa | |
| KIF21A-4949HCL | Recombinant Human KIF21A 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
KIF21A involved in several pathways and played different roles in them. We selected most pathways KIF21A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KIF21A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
KIF21A has several biochemical functions, for example, ATP binding,ATPase activity,microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KIF21A itself. We selected most functions KIF21A had, and list some proteins which have the same functions with KIF21A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase activity | DNAH6,ABCB6A,PEX6,PSMD6,KIF22,ABCF2A,KIF1B,ABCG2D,ASNA1,KIF14 |
| microtubule binding | MAST2,FGF13,MAPRE3A,CAMSAP1B,KIF14,KIF26A,PRC1A,ARHGEF2,DPYSL5,CASC1 |
| ATP binding | HK2,MUSK,CAMK2B,ACTR1,SYN1,PIP5KL1,BMPR1B,PFKFB4L,ADCY8,HK1 |
| microtubule motor activity | KIF23,KIF3B,DNAH11,KIF4,DYNC1LI1,KIF2C,KIFC1,KLC1A,KIF5B,KIF5AA |
| protein binding | LRRK2,IKZF1,HDAC4,CCDC167,SLC35F6,TBX22,BCCIP,ERLEC1,SRSF2,MICAL1 |
Interacting Protein
KIF21A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIF21A here. Most of them are supplied by our site. Hope this information will be useful for your research of KIF21A.
KANK1;ARFGEF1;ZNF24;KANK1;NCOA4;TACC2;PHRF1;Kif21b;MAP3K4;TBX3;NVL;PFDN1;ENDOD1
Resources
Related Services
Related Products
References
- Ni, CZ; Wang, CY; et al. Detection of the quantity of kinesin and microgravity-sensitive kinesin genes in rat bone marrow stromal cells grown in a simulated microgravity environment. ACTA ASTRONAUTICA 68:1722-1728(2011).
- Shen, XY; Meza-Carmen, V; et al. Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:18788-18793(2008).
