KDM4B
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Official Full Name
lysine (K)-specific demethylase 4B -
Overview
KDM4B / JMJD2B is a jumonji domain containing histone demethylase that specifically demethylates histone H3 at K9 and K36. -
Synonyms
KDM4B;lysine (K)-specific demethylase 4B;JMJD2B;TDRD14B;lysine-specific demethylase 4B;tudor domain containing 14B;jumonji domain containing 2B;jumonji domain-containing protein 2B;jmjC domain-containing histone demethylation protein 3B
Recombinant Proteins
- Rhesus macaque
- Mouse
- Zebrafish
- Human
- Mammalian Cells
- Sf9 Cells
- HEK293
- His
- GST
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KDM4B-2382R | Recombinant Rhesus monkey KDM4B Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| Kdm4b-260M | Recombinant Mouse Kdm4b, GST-tagged | Sf9 Cells | Mouse | GST | 1-725 a.a. |
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| KDM4B-5215Z | Recombinant Zebrafish KDM4B | Mammalian Cells | Zebrafish | His |
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| KDM4B-953H | Recombinant Human KDM4B | Mammalian Cells | Human | His |
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| KDM4B-4995HCL | Recombinant Human KDM4B 293 Cell Lysate | HEK293 | Human | Non |
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| KDM4B-2203R | Recombinant Rhesus Macaque KDM4B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| KDM4B-2203R-B | Recombinant Rhesus Macaque KDM4B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| KDM4B-3198H | Recombinant Human KDM4B Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| KDM4B-3198H-B | Recombinant Human KDM4B Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
KDM4B involved in several pathways and played different roles in them. We selected most pathways KDM4B participated on our site, such as Chromatin modifying enzymes,Chromatin organization,DNA Double Strand Break Response, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks | EYA2,EYA4,EYA3,BAZ1B,KDM4A |
| DNA Double-Strand Break Repair | HUS1,RBBP8,TOPBP1,KIAA0146,BRCC3,UBE2V2,TDP2,RAD9B,RAD50,HTATIP |
| DNA Repair | NFRKB,RBBP8,CHD1L,ZFP830,TFPT,BARD1,INO80,RAD9B,ZBTB32,DCLRE1A |
| HDMs demethylate histones | JHDM1D,KDM1B,KDM5BB,KDM6B,KDM7AB,KDM5B,KDM5D,KDM6AL,KDM4A,KDM2B |
| Chromatin modifying enzymes | NCOA2,SMARCB1B,KAT7B,CARM1,PBRM1,MORF4L1,COPRS,SMARCC1B,ACTL6A,TADA2A |
| Chromatin organization | EPC1,KDM4D,MBD3A,SMARCC1B,MSL1A,MSL2B,PHF2,PRMT5,MCRS1,KAT7B |
| DNA Double Strand Break Response | RAD50,HTATIP,TP53BP1,EYA3,UIMC1,SMARCA5,BRE,EYA2,FAM175A,KDM4A |
Protein Function
KDM4B has several biochemical functions, for example, dioxygenase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KDM4B itself. We selected most functions KDM4B had, and list some proteins which have the same functions with KDM4B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | Car8,ESRRG,ZFML,MLL5,CPB2,RAI1,RNF151,GATA2B,ADH5,TRIM65 |
| dioxygenase activity | KDM5D,ALOX5A,KDM3A,JMJD5,JMJD1C,PHF2,PTGS2,TDO2B,LEPREL1,OGFOD3 |
Interacting Protein
KDM4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM4B here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM4B.
HIST2H4B;GAMMAHV.ORF31;SF1;H3F3C;MED10;CHORDC1
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References
- Qu, BB; Liu, OS; et al. Distal-less homeobox 2 promotes the osteogenic differentiation potential of stem cells from apical papilla. CELL AND TISSUE RESEARCH 357:133-143(2014).
