KDM3B
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Official Full Name
lysine (K)-specific demethylase 3B -
Overview
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. Lysine-specific demethylase 3B is an enzyme that in humans is encoded by the KDM3B gene. -
Synonyms
KDM3B;lysine (K)-specific demethylase 3B;5qNCA;NET22;C5orf7;JMJD1B;lysine-specific demethylase 3B;nuclear protein 5qNCA;jumonji domain containing 1B;jumonji domain-containing protein 1B;jmjC domain-containing histone demethylation protein 2B;KIAA1082;OTTHUMP00000224009
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| KDM3B-302H | Recombinant Human KDM3B, His-tagged | E.coli | Human | His | 1127-1382aa | |
| KDM3B-49H |
Active Recombinant Human KDM3B, FLAG-tagged
|
Sf9 Insect Cell | Human | Flag |
|
|
| KDM3B-1266H | Recombinant Human KDM3B Protein, His-SUMO/MYC-tagged | E.coli | Human | His&Myc&SUMO | 1498-1721 a.a. |
|
| KDM3B-2123HCL | Recombinant Human KDM3B cell lysate | Human | Non |
|
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| KDM3B-2358H | Recombinant Human KDM3B Protein, His-tagged | E.coli | Human | His | Met1498-Arg1721 |
|
Involved Pathway
KDM3B involved in several pathways and played different roles in them. We selected most pathways KDM3B participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HDMs demethylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with KDM3B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HDMs demethylate histones | KDM5BA,KDM7AB,KDM5C,KDM1B,KDM4D,KDM5A,PHF2,JMJD6,KDM2B,KDM5D |
| Chromatin organization | PADI3,KDM3A,CHD4,KDM4D,MSL2B,KDM5BA,SMYD3,PADI1,DNMT3A,EPC1 |
| Chromatin modifying enzymes | KDM3A,KANSL3,KDM4A,MBIP,CCDC101,KAT7,BRPF1,MTA2,MSL2A,JHDM1D |
Protein Function
KDM3B has several biochemical functions, for example, antioxidant activity,dioxygenase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KDM3B itself. We selected most functions KDM3B had, and list some proteins which have the same functions with KDM3B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF740B,GNAL,ZSCAN4F,TRAFD1,ZHX3,FURIN,LATS2,KLF7A,DMRT1,GMEB1 |
| antioxidant activity | S100A9,APOA4,MT3,PRDX2,APOE,UBIAD1,CAT,SEPW1,TP53INP1,TRP53INP1 |
| dioxygenase activity | P4HA1B,ALOX5B.3,KDM6B,JMJD5,HPDA,ADOB,PHF2,ASPHD1,ALOX8,ADOA |
Interacting Protein
KDM3B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KDM3B here. Most of them are supplied by our site. Hope this information will be useful for your research of KDM3B.
USP18;ZNF512B;SPAG8;AK1;MYH9;LMNB2;DEPDC1
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