KAT7

  • Official Full Name

    K(lysine) acetyltransferase 7

  • Overview

    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

  • Synonyms

    KAT7;K(lysine) acetyltransferase 7;HBO1;HBOA;MYST2;ZC2HC7;histone acetyltransferase KAT7;MYST-2;lysine acetyltransferase 7;histone acetyltransferase MYST2;MYST histone acetyltransferase 2;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2;histone acetyltransferase binding to ORC1

Recombinant Proteins

  • Human
  • Rat
  • Sf9 Cells
  • Mammalian Cells
  • HEK293
  • E.coli
  • Wheat Germ
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Fc&Avi
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
KAT7-1601H Recombinant Human K(Lysine) Acetyltransferase 7, GST-tagged Sf9 Cells Human GST
KAT7-3157R Recombinant Rat KAT7 Protein Mammalian Cells Rat His
KAT7-6956H Recombinant Human KAT7 , GST-tagged Sf9 Cells Human GST Full length
KAT7-3999HCL Recombinant Human MYST2 293 Cell Lysate HEK293 Human Non
KAT7-1200H Recombinant Human KAT7 Protein (1-214 aa), GST-tagged E.coli Human GST 1-214 aa
KAT7-2813R Recombinant Rat KAT7 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
KAT7-2813R-B Recombinant Rat KAT7 Protein Pre-coupled Magnetic Beads HEK293 Rat
KAT7-5864H Recombinant Human KAT7 Protein, GST-tagged Wheat Germ Human GST
KAT7-6627HF Recombinant Full Length Human KAT7 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 611 amino acids
KAT7-6957H Recombinant Human KAT7 protein, Flag-tagged Sf9 Cells Human Flag

    Involved Pathway

    KAT7 involved in several pathways and played different roles in them. We selected most pathways KAT7 participated on our site, such as Androgen receptor signaling pathway,Chromatin modifying enzymes,Chromatin organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with KAT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization PBRM1,ATF7IP,SUZ12B,PADI3,MSL1,ASH2L,ING5B,SMARCB1,ACTL6A,EP400
    Androgen receptor signaling pathway NR0B2A,KDM1A,CTNNB2,MYST2,CTNNB1,POU2F1B,KAT7B,EGFR,HMGB2A,RANBP9
    Regulation of Androgen receptor activity NR2C2,SRY,HOXB13,SENP1,NR2C1,SMARCE1,GATA2,NR0B1,SPDEF,APPBP2
    HATs acetylate histones ELP2,TADA3,MBIP,CAPNS2,BRD1,KIAA1267,ANO9A,MSL2A,TADA1,PAX3A
    Chromatin modifying enzymes KDM3B,SMARCA4,HMG20B,TAF6L,DMAP1,SMARCB1,ARID4A,SMARCC1,SAP30,RUVBL2

    Protein Function

    KAT7 has several biochemical functions, for example, histone acetyltransferase activity,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KAT7 itself. We selected most functions KAT7 had, and list some proteins which have the same functions with KAT7. You can find most of the proteins on our site.

    Function Related Protein
    protein binding AP2B1,TUBB2B,UBE2M,NDFIP1,BAG2,AP4B1,ARNTL1A,AURKAIP1,COX5A,CST3
    transcription factor activity, sequence-specific DNA binding SIM1B,CLOCK,ATOH1,ATF4B2,TAF5L,ZFP746,MEOX1,ZNF8,ETS1,ZFP28
    histone acetyltransferase activity CREBBP,KAT8,NCOA3,TAF1L,KAT7A,vnc,CSRP2BP,MGEA5,METTL8,KAT5
    zinc ion binding LNX2B,SEC23A,THRB,RNF13,RNF114,MT1G,MYLIP,AMFR,BHMT,FAM90A1

    Interacting Protein

    KAT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KAT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of KAT7.

    VIM;CDK11B;AR;BARD1;CEP126

    Resources

    Research Area

    Histone Acetyltransferases and Associated Proteins

    References

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