ITPA
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Official Full Name
inosine triphosphatase (nucleoside triphosphate pyrophosphatase) -
Synonyms
ITPA;inosine triphosphatase (nucleoside triphosphate pyrophosphatase);C20orf37;inosine triphosphate pyrophosphatase;dJ794I6.3;HLC14 06 P;NTPase;My049 protein;inosine triphosphatase-A;putative oncogene protein HLC14-06-P;nucleoside triphosphate diphosphatase;nucleoside-triphosphate diphosphatase;non-standard purine NTP pyrophosphatase;nucleoside-triphosphate pyrophosphatase;non-canonical purine NTP pyrophosphatase;inosine triphosphate pyrophosphohydrolase;ITPase;HLC14-06-P
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
ITPA involved in several pathways and played different roles in them. We selected most pathways ITPA participated on our site, such as Drug metabolism - other enzymes,Metabolic pathways,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | RRM2,NT5M,POLR3E,POLR2F,POLR1D,UPRT,NME6,POLR3GL,POLR3D,TK1 |
| Metabolism of nucleotides | DPYDA.1,PROZA,DUT,DCK,ADAL,NUDT16,ADSSL1,TYMP,ADA,ADSL |
| Metabolic pathways | NME7,PTDSS2,MDH1AA,NT5C3A,CYP7A1,PANK1,AGL,ALOX15B,IDI1,AHCY |
| Drug metabolism - other enzymes | UCK2,UGT1A1,CES1,UGT1AB,IMPDH2,UMPS,UGT1A6,UGT1A2,DPYD,CES2 |
| Purine metabolism | NTPCR,AK5,POLR3GLB,POLR3F,NUDT9,PNP6,RRM2,POLD1,ADPRM,PNP5A |
| Metabolism | DPYD,ARSJ,CYP4F11,PPM1LA,PNP5B,ARSE,ATP5S,CYP3A7,FAAH2,PLCD3 |
Protein Function
ITPA has several biochemical functions, for example, ITP diphosphatase activity,XTP diphosphatase activity,dITP diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPA itself. We selected most functions ITPA had, and list some proteins which have the same functions with ITPA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| XTP diphosphatase activity | NUDT19,DOM3Z |
| metal ion binding | KLF14,ATP2B1B,UBA2,MOB2,ALKBH7,GNAZ,MAP3K15,RNF220A,CYP2X9,MKNK2 |
| nucleotide binding | ABCA4A,HSC70,PRAC,DHRS3,NTRK2B,UBE2IA,SMC2,GNA15.4,ARF3B,SRSF1A |
| dITP diphosphatase activity | DOM3Z,NUDT19,NUDT16 |
Interacting Protein
ITPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPA here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPA.
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