ITIH5
-
Official Full Name
inter-alpha-trypsin inhibitor heavy chain family, member 5 -
Overview
This gene encodes a heavy chain component of one of the inter-alpha-trypsin inhibitor (ITI) family members. ITI proteins are involved in extracellular matrix stabilization and in the prevention of tumor metastasis. They are also structurally related plasma serine protease inhibitors and are composed of a light chain and varying numbers of heavy chains. This family member is thought to function as a tumor suppressor in breast and thyroid cancers. Alternative splicing results in multiple transcript variants. -
Synonyms
ITIH5;inter-alpha-trypsin inhibitor heavy chain family, member 5;inter alpha (globulin) inhibitor H5;inter-alpha-trypsin inhibitor heavy chain H5;MGC10848;ITI heavy chain H5;inter-alpha (globulin) inhibitor H5;inter-alpha-inhibitor heavy chain 5;I
Recombinant Proteins
- Mouse
- Human
- E.coli
- Mammalian Cells
- HEK293
- His
- His&SUMO
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ITIH5-8378M | Recombinant Mouse Itih5 protein, His-tagged | E.coli | Mouse | His | Asp569~Gln737 |
|
| ITIH5-955H | Recombinant Human ITIH5 | Mammalian Cells | Human | His |
|
|
| ITIH5-1051H | Recombinant Human ITIH5 Protein (35-161 aa), His-SUMO-tagged | E.coli | Human | His&SUMO | 35-161 aa |
|
| ITIH5-1222H | Recombinant Human ITIH5 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| ITIH5-1222H-B | Recombinant Human ITIH5 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| ITIH5-2345H | Recombinant Human ITIH5 Protein, His-tagged | E.coli | Human | His | Gln251-Asn508 |
|
| ITIH5-2593H | Recombinant Human ITIH5 Protein (Gln251-Asn508), His tagged | E.coli | Human | His | Gln251-Asn508 |
|
| ITIH5-992HFL | Recombinant Full Length Human ITIH5 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
|
Involved Pathway
ITIH5 involved in several pathways and played different roles in them. We selected most pathways ITIH5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ITIH5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ITIH5 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITIH5 itself. We selected most functions ITIH5 had, and list some proteins which have the same functions with ITIH5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase inhibitor activity | SERPINB1C,SERPINI1,SERPINB1B,APP,APPA,COL28A1,COL7A1,HRG,APLP2,SERPINA5 |
Interacting Protein
ITIH5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITIH5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITIH5.
Resources
Related Services
Related Products
References
- Veeck, J; Chorovicer, M; et al. The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation. ONCOGENE 27:865-876(2008).
