ITGB1BP1
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Official Full Name
integrin beta 1 binding protein 1 -
Overview
The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. -
Synonyms
ITGB1BP1;integrin beta 1 binding protein 1;integrin beta-1-binding protein 1;bodenin;ICAP 1A;ICAP 1alpha;ICAP 1B;ICAP1;ICAP1A;ICAP1B;integrin cytoplasmic domain associated protein 1;integrin cytoplasmic domain associated protein 1 alpha;integrin cytoplasmic domain associated protein 1 beta;DKFZp686K08158;ICAP 1;ICAP-1;Integrin cytoplasmic domain-associated protein 1;ITBP1_HUMAN;OTTHUMP00000115481;OTTHUMP00000115482;OTTHUMP00000195584;OTTHUMP00000195586;OTTHUMP00000214081;OTTHUMP00000214082;OTTHUMP00000214088;integrin cytoplasmic dom;ICAP-1A;ICAP-1B;ICAP-1alpha
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ITGB1BP1-177H | Recombinant Human ITGB1BP1, GST-tagged | E.coli | Human | GST | 8-200aa | |
| ITGB1BP1-3530Z | Recombinant Zebrafish ITGB1BP1 | Mammalian Cells | Zebrafish | His |
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| ITGB1BP1-5316C | Recombinant Chicken ITGB1BP1 | Mammalian Cells | Chicken | His |
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| ITGB1BP1-8362M | Recombinant Mouse ITGB1BP1 Protein | Mammalian Cells | Mouse | His |
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| ITGB1BP1-5126HCL | Recombinant Human ITGB1BP1 293 Cell Lysate | HEK293 | Human | Non |
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| ITGB1BP1-2647H | Recombinant Human ITGB1BP1 Protein, His-tagged | E.coli | Human | His |
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| ITGB1BP1-4643M | Recombinant Mouse ITGB1BP1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ITGB1BP1-4643M-B | Recombinant Mouse ITGB1BP1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ITGB1BP1-4985H | Recombinant Human ITGB1BP1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ITGB1BP1-5761HF | Recombinant Full Length Human ITGB1BP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 200 amino acids |
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Involved Pathway
ITGB1BP1 involved in several pathways and played different roles in them. We selected most pathways ITGB1BP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGB1BP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ITGB1BP1 has several biochemical functions, for example, GDP-dissociation inhibitor activity,integrin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGB1BP1 itself. We selected most functions ITGB1BP1 had, and list some proteins which have the same functions with ITGB1BP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | SV2A,PRKAG2,EEF1A2,KCNH1,SREBF1,NBEA,DCX,LAT,TRAF4,SFN |
| integrin binding | FBN1,THBS1,AMICA1,ADAMTS8,ICAM3,ITGA5,ADAM22,ICAM4,FAP,JAM3 |
| protein transporter activity | RAMP2,RAMP1,TNPO1,AP2A1,COG2,EIF4ENIF1,SEC61G,VPS26B,L7RN6,CALCR |
| protein complex binding | KHDRBS1,RAD18,TAB1,KAT2B,NFKBIA,KLHL8,VHLL,WASF1,MYC,CDK4 |
| GDP-dissociation inhibitor activity | SH3BP4A,GPSM1,GPSM1B,GDI1,GPSM2L,RANBP1,RGS14,SH3BP4 |
| protein binding | CAMP,STYK1,CNPY2,RPSA,SAV1,TBC1D15,FAM115A,PIP5K1B,RAB27A,ZFPM1 |
Interacting Protein
ITGB1BP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGB1BP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGB1BP1.
pgrmc1;FIGNL1;KRIT1;DFNA5;UTRN;EEF1A1;SLC35F5;FAF1
Resources
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References
- Wang, XZ; Maynard, JA; et al. The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies. JOURNAL OF BIOLOGICAL CHEMISTRY 290:3576-3591(2015).
- Green, CJ; Fraser, ST; et al. Insulin-like growth factor 1 increases apical fibronectin in blastocysts to increase blastocyst attachment to endometrial epithelial cells in vitro. HUMAN REPRODUCTION 30:284-298(2015).
