ITGA9

  • Official Full Name

    integrin, alpha 9

  • Overview

    This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]

  • Synonyms

    ITGA9;integrin, alpha 9;RLC;ITGA4L;ALPHA-RLC;integrin alpha-9;integrin alpha-RLC

Recombinant Proteins

  • Human
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Wheat Germ
  • His
  • Non
  • GST
  • Myc&DDK
  • His&GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
ITGA9-176H Recombinant Human ITGA9, His-tagged E.coli Human His 12-352aa
ITGA9-2077C Recombinant Chicken ITGA9 Mammalian Cell Chicken His
ITGA9-5130HCL Recombinant Human ITGA9 293 Cell Lysate HEK293 Human Non
ITGA9-1236H Recombinant Human ITGA9 protein, GST-tagged E.coli Human GST 462-613 aa
ITGA9-2053H Recombinant Human ITGA9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
ITGA9-247H Recombinant Human ITGA9 Protein, His/GST-tagged E.coli Human His&GST Val741~Val965
Itga9-248M Recombinant Mouse Itga9 Protein, His/GST-tagged E.coli Mouse His&GST Ser788~Asp1030
Itga9-251M Recombinant Mouse Itga9 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
ITGA9-4992H Recombinant Human ITGA9 Protein, GST-tagged Wheat Germ Human GST

    Involved Pathway

    ITGA9 involved in several pathways and played different roles in them. We selected most pathways ITGA9 participated on our site, such as PIK-Akt signaling pathway,Focal adhesion,ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITGA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Focal adhesion ITGA3,PPP1R12A,CAV1,TLN2A,LAMA3,ITGA1,TNXB,MAPK4,ITGA10,PRKCB
    Cell adhesion molecules (CAMs) MHC2DAB,NLGN3,BLA,CLDN15LA,CLDN5A,BLB2,HLA-DRB3,ITGA4,CDH3,JAM2
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) ITGA3,ITGA4,CACNG7,ITGB5,CACNB3,SGCB,SLC8A1,ACTN3,SGCA,ITGA2B
    Regulation of Actin Cytoskeleton BCAR1,CYFIP2,PFN1,MYLK4,CHRM5A,RAC1A,PDGFD,FGFR4,KRAS,ITGA5
    Hypertrophic cardiomyopathy (HCM) TTN,ITGA1,CACNB3,ITGB3,TPM1,PRKAG2,ATP2A2,CACNA2D3,CACNG4,MYL3
    ECM-receptor interaction ITGA2,ITGB8,SV2A,ITGB1B.2,COL2A1,COL4A4,COL6A3,ITGA6B,LAMA4,IBSP
    PIK-Akt signaling pathway GNG7,PDGFC,Reln,PDPK1,IFNA7,PPP2R2B,IRS1,ANGPT4,LAMA2,GNG4
    Dilated cardiomyopathy TNNI3,CACNG3,GNAS,MYBPC3,CACNA2D2,IGF1,DMD,TGFB1,ADRB1,Itga10&Itgb1

    Protein Function

    ITGA9 has several biochemical functions, for example, collagen binding,laminin binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ITGA9 itself. We selected most functions ITGA9 had, and list some proteins which have the same functions with ITGA9. You can find most of the proteins on our site.

    Function Related Protein
    laminin binding TINAGL1,CTSS,ITGA3,ACHE,LYPD3,LGALS2A,NID1,GPC1,LGALS1,ECM1
    metal ion binding FOXP1,GNA12,MYLIPB,RIOK1,MOXD1L,OVOL3,TGM5,CYP2B19,ADHFE1,ZNF461
    collagen binding HSD17B12,SERPINH2,ITGA1,Itga10&Itgb1,LUM,ASPN,ACHE,MTAP1A,Pdgfa&Pdgfb,USH2A

    Interacting Protein

    ITGA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITGA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITGA9.

    Resources

    Research Area

    Integrins
    Integrins in Focal Adhesions
    Basolateral Molecules

    References

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