ISCA2
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Official Full Name
iron-sulfur cluster assembly 2 homolog (S. cerevisiae) -
Synonyms
ISCA2;iron-sulfur cluster assembly 2 homolog (S. cerevisiae);HBLD1, HesB like domain containing 1;iron-sulfur cluster assembly 2 homolog, mitochondrial;ISA2;iron sulfur cluster assembly 2 homolog (S. cerevisiae);mitochondrial;c14_5557;HESB like domain containing 1;HESB like domain containing protein 1;HESB-like domain-containing protein 1;Iron sulfur cluster assembly 2 homolog, mitochondrial;Iron-sulfur cluster assembly 2 homolog;ISCA2_HUMAN;HBLD1
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
ISCA2 involved in several pathways and played different roles in them. We selected most pathways ISCA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ISCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ISCA2 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding,4 iron, 4 sulfur cluster binding,ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ISCA2 itself. We selected most functions ISCA2 had, and list some proteins which have the same functions with ISCA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 2 iron, 2 sulfur cluster binding | AOX3L1,AOX4,FDX1B,RFESD,ISCA1,SDHB,CISD1,CISD2,XDH,AIFM3 |
| protein binding | GSTM5,GRIN2C,ERO1L,NUP37,CXCL11,HSPBP1,ENSA,RPL19,DUSP14,GNPDA2 |
| ferrous iron binding | TH,ALKBH3,DNAJC24,ALKBH2,EGLN2,CDO1,Trf,ACP5,BCO1,ALKBH1 |
| structural molecule activity | LAMB2,CYT1L,OC90,CLDN4,ADD1,CLDN10,KRT83,JUP,SNTG1,TUBB5 |
| 4 iron, 4 sulfur cluster binding | ETFDH,BRIP1,SDHB,NDUFS8A,NTHL1,NUBPL,ISCU,NDUFS2,ACO2,DNA2 |
Interacting Protein
ISCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ISCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ISCA2.
RNF41
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References
- Al-Hassnan, ZN; Al-Dosary, M; et al. ISCA2 mutation causes infantile neurodegenerative mitochondrial disorder. JOURNAL OF MEDICAL GENETICS 52:186-194(2015).
- Alazami, AM; Patel, N; et al. Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families. CELL REPORTS 10:148-161(2015).
