IQGAP2
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Official Full Name
IQ motif containing GTPase activating protein 2 -
Overview
IQGAPs are scaffolding proteins involved in mediating cytoskeletal function. They contain multiple protein interaction domains and bind to a growing number of molecules including actin, myosin light chain, calmodulin, E-cadherin, and beta-catenin. Through -
Synonyms
IQGAP2;IQ motif containing GTPase activating protein 2;ras GTPase-activating-like protein IQGAP2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| IQGAP2-24H | Recombinant Human IQGAP2 protein, GST-tagged | Wheat Germ | Human | GST | 343-449 a.a. |
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| IQGAP2-5140C | Recombinant Chicken IQGAP2 | Mammalian Cells | Chicken | His |
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| IQGAP2-6853Z | Recombinant Zebrafish IQGAP2 | Mammalian Cells | Zebrafish | His |
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| IQGAP2-001H | Recombinant Human IQ motif containing GTPase activating protein 2 Protein, His-tagged | E.coli | Human | His | 444-633aa |
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| IQGAP2-10H | Recombinant Human IQGAP2 protein(519-727 aa), His-tagged | E.coli | Human | His | 519-727 aa |
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| IQGAP2-11H | Recombinant Human IQGAP2 protein(231-530 aa), His-tagged | E.coli | Human | His | 231-530 aa |
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Involved Pathway
IQGAP2 involved in several pathways and played different roles in them. We selected most pathways IQGAP2 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with IQGAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | APC2,PPP1CAB,CHRM2A,ITGAM,PPP1R12C,FGFR1A,PIK3R3,MSN,CDC42L,SSH2 |
Protein Function
IQGAP2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by IQGAP2 itself. We selected most functions IQGAP2 had, and list some proteins which have the same functions with IQGAP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
IQGAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IQGAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of IQGAP2.
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References
- Tseng, PC; Chen, CL; et al. An increase in integrin-linked kinase non-canonically confers NF-kappa B-mediated growth advantages to gastric cancer cells by activating ERK1/2. CELL COMMUNICATION AND SIGNALING 12:-(2014).
- Ma, YY; Jin, ZX; et al. Quercetin suppresses the proliferation of multiple myeloma cells by down-regulating IQ motif-containing GTPase activating protein 1 expression and extracellular signal-regulated kinase activation. LEUKEMIA & LYMPHOMA 55:2597-2604(2014).
