IPO8
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Official Full Name
importin 8 -
Synonyms
IPO8;importin 8;importin-8;Imp 8;Imp8;Importin8;IPO 8;Ran binding protein 8;RAN BP8;RANBP 8;RANBP8
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- GST
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Ipo8-199M | Recombinant Mouse Ipo8 Protein, His/GST-tagged | E.coli | Mouse | GST&His | Tyr417~Val622 |
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| IPO8-2286R | Recombinant Rhesus monkey IPO8 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| IPO8-3874Z | Recombinant Zebrafish IPO8 | Mammalian Cells | Zebrafish | His |
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| IPO8-8266M | Recombinant Mouse IPO8 Protein | Mammalian Cells | Mouse | His |
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| IPO8-2107R | Recombinant Rhesus Macaque IPO8 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| IPO8-2107R-B | Recombinant Rhesus Macaque IPO8 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| IPO8-4583M | Recombinant Mouse IPO8 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| IPO8-4583M-B | Recombinant Mouse IPO8 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| IPO8-5075H | Recombinant Human IPO8 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
IPO8 involved in several pathways and played different roles in them. We selected most pathways IPO8 participated on our site, such as Gene Expression,Gene Silencing by RNA,Transcriptional regulation by small RNAs, which may be useful for your reference. Also, other proteins which involved in the same pathway with IPO8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gene Silencing by RNA | TARBP2,TNRC6B,MAEL,TSN,DDX4,EIF2C3,AGO3B,DGCR8,TSNAX,FKBP6 |
| Transcriptional regulation by small RNAs | DPY19L2 |
| Gene Expression | MTERF,SNAPC3,ZNF383,ZNF136,NKX2,SF3B2,EIF1AX,ZNF620,ESRRGA,ZKSCAN4 |
Protein Function
IPO8 has several biochemical functions, for example, ATPase activity, coupled to transmembrane movement of substances,Ran GTPase binding,protein transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IPO8 itself. We selected most functions IPO8 had, and list some proteins which have the same functions with IPO8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein transporter activity | AP2B1,ITGB1BP1,DSCR3,AP2A2,COX18,KPNA4,VPS26BL,RAMP1,RANBP6,TNPO3 |
| Ran GTPase binding | RANBP2,XPOT,IPO11,RANBP1,IPO9,NUP153,RANGRF,IPO5,NXT1,RANBP10 |
| ATPase activity, coupled to transmembrane movement of substances | ABCA6,ABCG2,ABCA13,ABCB5,ABCD3B,ABCA1B,ABCA5,ABCG3,ABCC10,ABCB6 |
Interacting Protein
IPO8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IPO8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IPO8.
Irs1;Rpgrip1l
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References
- Moriyama, T; Mizuguchi, C; et al. Generation of Rat Monoclonal Antibody Specific for Mouse Importin alpha 8. HYBRIDOMA 30:303-306(2011).
- Yoneda, Y; et al. Monoclonal Antibody 3F2 Against Mouse Importin alpha 8. HYBRIDOMA 30:315-315(2011).
- Pryor, MJ; Rawlinson, SM; et al. Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection. TRAFFIC 8:795-807(2007).
- Subramaniam, PS; Larkin, J; et al. The COOH-terminal nuclear localization sequence of interferon gamma regulates STAT1 alpha nuclear translocation at an intracellular site. JOURNAL OF CELL SCIENCE 113:2771-2781(2000).
