INSL5
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Official Full Name
insulin-like 5 -
Overview
The protein encoded by this gene contains a classical signature of the insulin superfamily and is highly similar to relaxin 3 (RLN3/INSL7). -
Synonyms
INSL5;insulin-like 5;insulin-like peptide INSL5;insulin-like peptide 5;PRO182;UNQ156;MGC126695;MGC126697
Recombinant Proteins
- Mouse
- Human
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&GST
- Non
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Insl5-1049M | Recombinant Mouse Insl5 protein, His & GST-tagged | E.coli | Mouse | His&GST | Arg23~Cys135 |
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| INSL5-228H | Recombinant Human INSL5 Protein | E.coli | Human | Non |
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| INSL5-5190HCL | Recombinant Human INSL5 293 Cell Lysate | HEK293 | Human | Non |
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| INSL5-2274H | Recombinant Human INSL5 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| INSL5-301251H | Recombinant Human INSL5 protein, GST-tagged | E.coli | Human | GST | His49-Cys135 |
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| Insl5-3554M | Recombinant Mouse Insl5 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| INSL5-5095H | Recombinant Human INSL5 Protein, GST-tagged | Wheat Germ | Human | GST |
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| INSL5-5987HF | Recombinant Full Length Human INSL5 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 135 amino acids |
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Involved Pathway
INSL5 involved in several pathways and played different roles in them. We selected most pathways INSL5 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with INSL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | HRH3,NPFFR2,QRFP,NTS,SSTR5,PPY,GPR37B,UTS2D,EDN3,DRD1 |
| Relaxin receptors | RLN2,RLN3,RXFP2,RLN3A,INSL3 |
| Peptide ligand-binding receptors | NTS,RLN3A,INSL3,EDN2,EDN3,PENKB,QRFPR,ACKR4,RLN3,CCL35.1 |
| G alpha (i) signalling events | RGS20,DRD4,SSTR3,TAS2R13,ANXA1A,ANXA1,OPN1MW2,AMCF-II,GAL,CCL19A.2 |
| Signaling by GPCR | PENKA,PYYA,PROK2,OXER1,CRHB,ADM2A,TAAR1,EMR4,OR7D2,GAL |
| Signal Transduction | GRK7,RSPO4,RGS14,TAC1,INSL3,OTULINB,GPR37B,RLN2,GPR68,FOXH1 |
| GPCR ligand binding | CXCR6,PROKR1A,ZFPM2B,TAS2R3,OXGR1A.3,RGR,CCR3,SST,PROKR2,GPR37B |
| GPCR downstream signaling | ADCYAP1,EDNRAB,ABHD6B,NPFFR2,RAMP2,OXGR1A.2,APPB,NPB,GPR17,CXCL11.8 |
Protein Function
INSL5 has several biochemical functions, for example, hormone activity. Some of the functions are cooperated with other proteins, some of the functions could acted by INSL5 itself. We selected most functions INSL5 had, and list some proteins which have the same functions with INSL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | RLN2,CHGB,UTS1,SMTLA,UCN2,SCT,CSH2,UTS2D,PRL2C3,RLN3 |
Interacting Protein
INSL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INSL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of INSL5.
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References
- Gremel, G; Wanders, A; et al. The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling. JOURNAL OF GASTROENTEROLOGY 50:46-57(2015).
- Yegorov, S; Bogerd, J; et al. The relaxin family peptide receptors and their ligands: New developments and paradigms in the evolution from jawless fish to mammals. GENERAL AND COMPARATIVE ENDOCRINOLOGY 209:93-105(2014).
