IMMP2L
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Official Full Name
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -
Overview
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. -
Synonyms
IMMP2L;IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae);IMP2 inner mitochondrial membrane protease like (S. cerevisiae);mitochondrial inner membrane protease subunit 2;IMP2;EC 3.4.21;IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae);IMP2 inner mitochondrial membrane protease like;IMP2 like;IMP2 like protein;Inner mitochondrial membrane peptidase 2 like;OTTHUMP00000207168;OTTHUMP00000207189;IMP2-LIKE
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Chicken
- Mouse
- zebrafish
- Xenopus laevis
- Mus musculus
- Bovine
- E.coli
- Mammalian Cells
- HEK293
- Wheat Germ
- His
- His&Fc&Avi
- GST
Involved Pathway
IMMP2L involved in several pathways and played different roles in them. We selected most pathways IMMP2L participated on our site, such as Protein export, which may be useful for your reference. Also, other proteins which involved in the same pathway with IMMP2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein export | SRP54B,SRP68,SPCS1,HSPA5,SRP54,SRP14,SRPR,SRP19,SLC38A8,OXA1L |
Protein Function
IMMP2L has several biochemical functions, for example, hydrolase activity,peptidase activity,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IMMP2L itself. We selected most functions IMMP2L had, and list some proteins which have the same functions with IMMP2L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity | MEP1A.1,ELA2,KLK1B1,TMEM62,DOM3Z,MEST,GNPDA2,TRY,TMPRSS7,CES1C |
| serine-type endopeptidase activity | PREP,Gzmd,MCPT1,MASP1,TMPRSS7,PCSK9,PIK3IP1,MST1,PRSS33,MCPT2 |
| serine-type peptidase activity | PLAUA,KLK1B16,PRSS42,TMPRSS11G,TMPRSS7,PRSS59.2,MCPT2,PRSS52,F9B,C1RA |
| peptidase activity | HTRA2,OTUD5A,REN,CASP8,ADAMTS4,HPN,STAMBPA,HTRA1A,AGBL4,CAPN8 |
Interacting Protein
IMMP2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IMMP2L here. Most of them are supplied by our site. Hope this information will be useful for your research of IMMP2L.
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References
- Ceroni, F; Simpson, NH; et al. Homozygous microdeletion of exon 5 in ZNF277 in a girl with specific language impairment. EUROPEAN JOURNAL OF HUMAN GENETICS 22:1165-1171(2014).
- Bertelsen, B; Melchior, L; et al. Intragenic deletions affecting two alternative transcripts of the IMMP2L gene in patients with Tourette syndrome. EUROPEAN JOURNAL OF HUMAN GENETICS 22:1283-1289(2014).
