ILKAP

  • Product List
  • Overview
  • Review / Q&A
  • Official Full Name

    integrin-linked kinase-associated serine/threonine phosphatase
  • Overview

    The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
  • Synonyms

    ILKAP;integrin-linked kinase-associated serine/threonine phosphatase;integrin linked kinase associated serine/threonine phosphatase 2C;integrin-linked kinase-associated serine/threonine phosphatase 2C;DKFZP434J2031;FLJ10181;protein phosphatase 2c, d

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • HEK293
  • E.coli
  • Mammalian Cells
  • Human Cells
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • DDK
  • Myc
  • Avi
  • Fc
  • SUMO
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
ILKAP-1126H Recombinant Human ILKAP protein(Met1-His392), His-tagged HEK293 Human His 1-392 a.a.
ILKAP-14217H Recombinant Human ILKAP, His-tagged E.coli Human His 1-392a.a.
ILKAP-3053R Recombinant Rat ILKAP Protein Mammalian Cells Rat His
ILKAP-8188M Recombinant Mouse ILKAP Protein Mammalian Cells Mouse His
ILKAP-1855HCL Recombinant Human ILKAP cell lysate Human Cells Human Non
ILKAP-147H Recombinant Full Length Human ILK associated serine/threonine phosphatase Protein, His tagged E.coli Human His Full L. 1-392aa
ILKAP-1677H Recombinant Human ILKAP Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
ILKAP-2174H Recombinant Human ILKAP Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
ILKAP-2709R Recombinant Rat ILKAP Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
ILKAP-2709R-B Recombinant Rat ILKAP Protein Pre-coupled Magnetic Beads HEK293 Rat
ILKAP-3111H Recombinant Human ILKAP protein, His-SUMO-tagged E.coli Human His&SUMO 1-392aa
Ilkap-3526M Recombinant Mouse Ilkap Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
ILKAP-4526M Recombinant Mouse ILKAP Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ILKAP-4526M-B Recombinant Mouse ILKAP Protein Pre-coupled Magnetic Beads HEK293 Mouse
ILKAP-5156H Recombinant Human ILKAP Protein, GST-tagged Wheat Germ Human GST
ILKAP-5797HF Recombinant Full Length Human ILKAP Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 392 amino acids

Involved Pathway

ILKAP involved in several pathways and played different roles in them. We selected most pathways ILKAP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ILKAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

Protein Function

ILKAP has several biochemical functions, for example, metal ion binding,protein binding,protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ILKAP itself. We selected most functions ILKAP had, and list some proteins which have the same functions with ILKAP. You can find most of the proteins on our site.

Function Related Protein
protein serine/threonine phosphatase activity CDC14A,PTEN,PPM1K,PPP1R15B,TIMM50,CDC14B,PPM1AA,UBLCP1,CDC14AA,PPA2
protein binding PSMD3,EIF5A2,CAV3,ADAMTS4,TRAPPC4,PNKD,C19orf80,THAP3,LRP2BP,PRKD3
metal ion binding ZFP541,B4GALT5,INSM1B,STK32B,ZNF567,MUSK,CYP3C4,ZNF10,MARCH11,DNTT

Interacting Protein

ILKAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ILKAP here. Most of them are supplied by our site. Hope this information will be useful for your research of ILKAP.

ILK;pi3p;15-deoxy-delta(12,14;LTN1;STAT5A;C21orf59;PDK1;CHST15;Wdr48;FBXO18;CERK

Resources

References

  • Arroyo-Berdugo, Y; Alonso, S; et al. Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma. PLOS ONE 9:-(2014).
  • Zhou, W; Cao, H; et al. Characterization of Nuclear Localization Signal in the N Terminus of Integrin-linked Kinase-associated Phosphatase (ILKAP) and Its Essential Role in the Down-regulation of RSK2 Protein Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY 288:6259-6271(2013).

Ask a Question for All ILKAP Products

Required fields are marked with *

My Review for All ILKAP Products

Required fields are marked with *